Merck
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TNF

tumor necrosis factor

别名:
DIF, TNF-alpha, TNFA, TNFSF2
物种:
UniProtKB ID:
基因ID:
  • Human(7124) Summary: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
  • Mouse(21926) tumor necrosis factor
  • Rat(24835) tumor necrosis factor
  • dog(403922) tumor necrosis factor
  • domestic cat(493755) tumor necrosis factor
  • Horse(100033834) tumor necrosis factor
  • Goat(100861232) tumor necrosis factor alpha
  • cow(280943) tumor necrosis factor
  • sheep(443540) tumor necrosis factor
  • Domestic Rabbit(100009088) tumor necrosis factor
  • domestic guinea pig(100135630) tumor necrosis factor
  • naked mole-rat(101718432) tumor necrosis factor

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ELISA

货号
说明
物种
大鼠肿瘤坏死因子α ELISA试剂盒, for serum, plasma and cell culture supernatant,
物种
rat
大鼠肿瘤坏死因子α ELISA试剂盒, for cell and tissue lysates,
物种
rat
恒河猴 TNFα/肿瘤坏死因子 αELISA 试剂盒, ,
物种
小鼠肿瘤坏死因子ELISA检测试剂盒, for serum, plasma and cell culture supernatant,
物种
mouse
牛TNF α /肿瘤坏死因子α -ELISA试剂盒, for serum, plasma and cell culture supernatants,
物种
cow

Small Molecule - Antagonist

货号
说明
物种
松香酸, technical, ~75% (GC),
物种
human
罗汉松酸, 98%,
物种
human
毛喉素, from Coleus forskohlii, ≥98% (HPLC), powder,
物种
human
SKF-86002, ≥98% (HPLC), solid,
物种
human, rat
杨梅黄素, ≥96.0%, crystalline,
物种
rat, mouse, human

Antibodies

货号
说明
物种反应性
应用
Anti-Tumor Necrosis Factor-α antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
dot blot
microarray

neutralization
兔抗-TNF-α抗体, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-TNF-α antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
抗TNFA 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry
Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse, clone 45418.111, purified immunoglobulin, lyophilized powder,
物种反应性
rat
应用
ELISA
neutralization

western blot

Small Molecule - Inhibitor

货号
说明
物种
SPD304, ≥98% (HPLC), solid,
物种
mouse, rat, human
SKF-86002, ≥98% (HPLC), solid,
物种
human, rat
杨梅黄素, ≥96.0%, crystalline,
物种
rat, mouse, human
杨梅黄素, ≥96.0% (HPLC),
物种
rat, mouse, human
普罗布考, analytical standard,
物种
human

Proteins

货号
说明
物种
肿瘤坏死因子-α 人, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
物种
human
肿瘤坏死因子-α 人, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
物种
human
肿瘤坏死因子-α蛋白,重组人类, Tumor Necrosis Factor-alpha (TNF-alpha) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells & certain other target cells.,
物种
human
肿瘤坏死因子-α 来源于大鼠, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
物种
rat
肿瘤坏死因子-α,人(hTNF-α), recombinant (yeast),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Tnf,
物种
mouse
MISSION® esiRNA, targeting human TNF,
物种
human