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Merck
CN

441511

N-Acetyl-L-leucine

99%, for peptide synthesis, ReagentPlus®

Synonym(s):

N-Acetyl-L-(-)-leucine, Acetylleucine

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NHCOCH3)CO2H
CAS Number:
1188-21-2
Molecular Weight:
173.21
NACRES:
NA.22
PubChem Substance ID:
24867665
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
214-706-3
MDL number:
MFCD00065131
Beilstein/REAXYS Number:
1724849

Key Documents

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Product Name

N-Acetyl-L-leucine, ReagentPlus®, 99%

InChI key

WXNXCEHXYPACJF-ZETCQYMHSA-N

InChI

1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1

SMILES string

CC(C)C[C@H](NC(C)=O)C(O)=O

product line

ReagentPlus®

assay

99%

form

solid

optical activity

[α]25/D −23±3°, c = 2 in ethanol

reaction suitability

reaction type: C-H Activation
reaction type: solution phase peptide synthesis
reagent type: catalyst
reaction type: Peptide Synthesis

mp

187-190 °C (lit.)

application(s)

peptide synthesis

functional group

amine
carboxylic acid

Quality Level

100

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ3091
MKCX5210
MKCW5674
MKCW5675
MKCT7899

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T Gopinath et al.
Journal of the American Chemical Society, 131(16), 5754-5756 (2009-04-09)
We present a new method for enhancing the sensitivity in static solid-state NMR experiments for a gain in signal-to-noise ratio of up to 40%. This sensitivity enhancement is different from the corresponding solution NMR sensitivity enhancement schemes and is achieved
Zhaoxiong Zheng et al.
Magnetic resonance in chemistry : MRC, 45 Suppl 1, S247-S260 (2007-12-25)
Two finite-pulse radiofrequency-driven recoupling (RFDR) methods were compared and applied to the measurement of 3-6 Å (13)CO-(13)CO distances in polycrystalline and membrane-associated HIV fusion peptide (HFP) samples. The RFDR methods were based on π pulses and were relatively straightforward to
D H Jones et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 179(1), 105-113 (2005-12-14)
Maximum Entropy reconstruction is applied to two-dimensional PISEMA spectra of stationary samples of peptide crystals and proteins in magnetically aligned virus particles and membrane bilayers. Improvements in signal-to-noise ratios were observed with minimal distortion of the spectra when Maximum Entropy
J Sun
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 13(3), 257-260 (1997-08-01)
The effects of acetyl-DL-leucine (AL) treatment (28 mg/kg.day, p.o.) on the vestibular compensation were studied over period of 6 weeks in unilateral vestibular neurectomized cats. This investigation was performed by measuring the recovery time of locomotor equilibrium in the rotating
Alexander A Nevzorov
Journal of magnetic resonance (San Diego, Calif. : 1997), 209(2), 161-166 (2011-02-08)
Cross-polarization transfer is employed in virtually every solid-state NMR experiment to enhance magnetization of low-gamma spins. Theory and experiment is used to assess the magnitude of the final quasistationary magnetization amplitude. The many-body density matrix equation is solved for relatively
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