ligand
(Sulfonic acid (cationic), t-butyl (HIC/hydrophobic))
Quality Level
material
housing (Copolymer of styrene and phenylene ether), membrane (Polyacrylamide hydrogel (microporous polymer) reinforced with polybutylene terephthalate substrate)
sterility
non-sterile
product line
Natrix®
parameter
≤10 MV/min max. flow rate, 5 bar pressure, 75 psi max. pressure
membrane volume
124 mL , nominal
matrix
Polyacrylamide hydrogel (microporous polymer) reinforced with polybutylene terephthalate substrate base material
pore size
1 μm pore size (diameter)
capacity
90 mg binding capacity (lysozyme/ml of membrane)(Up to 1000g/L load capacity in frontal mode)
application(s)
mAb
pharmaceutical
viral therapy
General description
It contains Natrix® CH membrane, a high-capacity cation exchange chromatography membrane.
Application
Bind-and-elute
Features and Benefits
- Unique Selectivity: excellent aggregate removal in flow-through mode.
- High Binding at Fast Flow-Rates: Natrix® CH membrane has 5x the binding capacity versus the competition at similar residence times.
- Ready to Process: saves time by eliminating the need for column packing required of traditional resins, simply prime the device and begin purifying.
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Regulatory Information
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Related Content
This document lists all the frequently asked questions about Natrix® CH devices.
The Natrix® CH chromatography membrane device achieves high binding capacity at fast flow rates for accelerated mAb purification.