79070
1-Phenyl-3-pyrazolidinone
purum, ≥98.0% (N)
Synonym(s):
Phenidone
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About This Item
Empirical Formula (Hill Notation):
C9H10N2O
CAS Number:
Molecular Weight:
162.19
EC Number:
202-155-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
131856
MDL number:
grade
purum
assay
≥98.0% (N)
mp
119-121 °C
solubility
methanol: 0.1 g/mL, clear
SMILES string
O=C1CCN(N1)c2ccccc2
InChI
1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)
InChI key
CMCWWLVWPDLCRM-UHFFFAOYSA-N
Gene Information
rat ... Alox5(25290)
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
275.5 °F - Pensky-Martens closed cup
flash_point_c
135.3 °C - Pensky-Martens closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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Hasan Tunaz
Archives of insect biochemistry and physiology, 63(3), 93-100 (2006-10-19)
Influence of fungal species (conidia spores) on mortality of Pieris brassicae larvae differed when injected into the larvae. The effects of B. bassiana (ARSEF-1151) were expressed in a conidial dose-dependent manner on mortality of the larvae. An increased and faster
C Audouin et al.
Bioorganic & medicinal chemistry letters, 11(6), 845-848 (2001-03-30)
N-Aminoindoline derivatives were prepared and their 5-lipoxygenase inhibitory activities were evaluated in vitro and compared with those of phenidone and NDGA. Compound 4 presents the most effective 5-LO inhibition.
Changjong Moon et al.
Brain research, 1035(2), 206-210 (2005-02-22)
This study examined whether phenidone, a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), affects the clinical symptoms of experimental autoimmune encephalomyelitis (EAE) in the rat, and the expression of both COX-1/-2 and 5-LOX in EAE spinal cords. Oral phenidone
T Sen et al.
Phytotherapy research : PTR, 16(4), 331-335 (2002-07-12)
Studies were carried out to evaluate the influence of the methanol fraction of Pluchea indica Less root extract (PIRE), the dual inhibitors (BW 755C and phenidone) and vitamin on both in vivo and in vitro free radical-scavenging activities, CCl(4)-induced lipid
Joonyup Kim et al.
FEBS letters, 587(2), 226-230 (2012-12-12)
It has previously been shown that jasmonic acid affects the ethylene signaling pathway. EIN2 is a central component of ethylene signaling that is downstream of the receptors. EIN2 has previously been shown to be required for ethylene responses. We found
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