P9159
Piperidine-4-sulfonic acid
Synonym(s):
P4S
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Empirical Formula (Hill Notation):
C5H11NO3S
CAS Number:
Molecular Weight:
165.21
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
form
powder
Quality Level
SMILES string
OS(=O)(=O)C1CCNCC1
InChI
1S/C5H11NO3S/c7-10(8,9)5-1-3-6-4-2-5/h5-6H,1-4H2,(H,7,8,9)
InChI key
UGBJGGRINDTHIH-UHFFFAOYSA-N
Gene Information
Related Categories
Biochem/physiol Actions
GABAA receptor agonist.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
G Maksay et al.
European journal of pharmacology, 411(1-2), 55-60 (2001-01-04)
In order to study the correlation of the thermodynamic driving forces of binding with the efficacies of displacing ligands, the specific binding of [3H]SR 95531 [2-(3-carboxypropyl)3-amino-6-p-methoxyphenylpyridazinium bromide], a GABA(A) receptor antagonist, was studied in cell lines stably expressing human alpha(1)beta(3)gamma(2)
Kate K O'Toole et al.
Molecular pharmacology, 81(2), 189-197 (2011-11-02)
The GABA type A receptor (GABA(A)R) is expressed ubiquitously throughout the brain and is a target for many therapeutic agents, including general anesthetics and benzodiazepines, which enhance receptor function by increasing the open probability (P(o)) of the ion channel. It
B Ebert et al.
Molecular pharmacology, 46(5), 957-963 (1994-11-01)
Using systematic combination of alpha 1, alpha 3, and alpha 5 with beta 1, beta 2, and beta 3, together with gamma 1, gamma 2, and gamma 3, we have investigated the contributions of the various alpha, beta, and gamma
G Akk et al.
The Journal of physiology, 532(Pt 3), 673-684 (2001-04-21)
Neurosteroids are produced in the brain, and can have rapid actions on membrane channels of neurons. Pregnenolone sulfate (PS) is a sulfated neurosteroid which reduces the responses of the [gamma]-aminobutyric acid A (GABA(A)) receptor. We analysed the actions of PS
Angelo Keramidas et al.
The Journal of physiology, 575(Pt 1), 11-22 (2006-06-10)
The binding of the neurotransmitter GABA induces conformational changes in the GABAA receptor (GABAAR), leading to the opening of a gate that controls ion permeation through an integral transmembrane pore. A number of structural elements within each subunit, located near
Articles
DISCOVER Bioactive Small Molecules for Neuroscience
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service