RN0100
Ribonuclease A Activity Kit
sufficient for 100 tests
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About This Item
NACRES:
NA.26
UNSPSC Code:
12352202
Product Name
Ribonuclease A Activity Kit, sufficient for 100 tests
usage
sufficient for 100 tests
storage temp.
2-8°C
Application
Ribonuclease A Activity Kit has been used to assess the activity of RNase released from the nanogels.
Biochem/physiol Actions
Ribonuclease A (RNase A) can convert RNA to oligonucleotides in the presence of water. In the absence of metal ions or cofactors, RNase A can catalyze the hydrolysis of single-stranded RNA.
General description
Ribonuclease A (RNase A), a well-known protein, is frequently used as a model system to study folding, stability, and chemistry. It is made up of three α helices and seven β strands that are organized in two "lobes".
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Lifelike but Not Living: Selection of Synthetically Modified Bioinspired Nucleic Acids for Binding and Catalysis
Perrin, D. M.
Polymer Science: A Comprehensive Reference (2012)
Xinghui Si et al.
Journal of controlled release : official journal of the Controlled Release Society, 320, 83-95 (2020-01-20)
As the most common malignancy in women, breast cancer causes >40,000 deaths annually. Ribonuclease A (RNase), a new anti-cancer agent, has attracted intense interest due to its high efficacy and specificity. However, RNase suffers from instability, a short half-life in
Predicting pKa Values with Continuous Constant pH Molecular Dynamics
Wallace JA and Shen JK
Methods in Enzymology (2009)
Bovine Pancreatic Ribonuclease A: Oxidative and Conformational Folding Studies
Scheraga HA, et al.
Methods in Enzymology (2001)
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