Mobius® single-use mixing solutions deliver efficient mixing of pharmaceutical ingredients from intermediate to final drug products, as well as preparation of process solutions such as buffers and media. Unlike traditional stainless steel mixers, single-use mixers reduce downtime spent on process steps such as cleaning in place (CIP), sterilization in place (SIP), cleaning validation, and process engineering. Mobius® single-use mixing solutions are capable of speeds up to 1000 RPM, meeting the broadest range of mixing production requirements. Mobius® flexibility offers you a choice of just the right filter, connector, and tubing options for your specific application and environment, including sterile interfaces, from fermentation to final fill.
Mobius® single-use mixing solutions include a complete range of mixers in sizes from 10 L to 3,000 L. Both Mobius® MIX and Mobius® Power MIX product lines offer proven operational efficiency, saving valuable processing and validation time. Our scalable, ready-to-use systems and processing technologies reduce the risk of contamination and deliver reproducible results.
Mobius® MIX: the mixing solution of choice for gentle mixing applications such as protein and shear-sensitive product homogenization
Mobius® Power MIX: the mixing solution of choice for hard-to-dissolve materials and buffer preparation
The Mobius® MIX family of single-use mixers is offered in sizes from 10 L to 1,000 L. Each single-use mixing container includes our proprietary, magnetically driven levitating impeller for improved mixing consistency and efficiency.
The Mobius® Power MIX family of single-use mixers combines high-performance mixing technology with design features that make it easy to use. The impeller design and motor are based on our magnetically coupled NovAseptic® mixing technology, a proven mixing technology used with stainless steel tanks for efficient mixing of the most challenging buffer, media, and biopharmaceutical ingredients.
Mobius® mixers can be monitored and controlled locally or remotely. Plug the ready to connect control box to the network and use Ethernet IP communication protocol to monitor speed, weight, temperature, pH and conductivity remotely. The ready to connect control box is a separate box on a four wheels chassis that can be easily moved around the Mobius® mixer carrier. Optimize your layout and get a better access to control your Mobius® mixing system by freely positioning the control box around it. The 21 CFR Part 11 compliant data recorder option displays data trends in real time and ensures process data integrity when recording.
In biomanufacturing processes, mixing is ubiquitous. Examples include buffer and media preparation, stirred tank bioreactor/fermentor operation, virus inactivation, DNA digestion, final formulation and beyond.
The Mobius® Power MIX single-use mixing systems combine high performance mixing technology with design features that make them easy-to-use. The impeller design and motor are based on our magnetically coupled NovAseptic® mixing technology, a proven mixing technology in stainless steel tanks.
The Mobius® Power MIX 2000 combines high performance mixing technology with design features that make it easy to use.
The Mobius® MIX single-use mixing solution delivers advanced technology for mixing pharmaceutical ingredients from intermediate to final drug products and for the preparation of process solutions, such as buffers and media.
Buffer preparation is a core operation of all biologics production processes. Buffers are used throughout processing from media preparation to final filtration, and although reliable buffer preparation is critical, the operation is often considered low added value.
The need for faster cycle times and higher levels of operational flexibility has accelerated the adoption of single-use processing solutions in the biopharmaceutical industry.
We provide comprehensive services for drug development and manufacturing, including technical and regulatory expertise and process development support.
The Mobius® Power MIX single-use systems provide an effective mixing platform for biopharmaceutical manufacturing in a range of sizes including 100, 200, 500, 1000 and 2000 L.
Mobius® Power MIX 100 is a 100 liter high performance, single-use mixing system targeted for small scale mixing in biopharmaceutical product/process development and manufacturing.
Mobius® Power MIX 200 is a 200 liter high performance, single-use mixing system targeted for small scale mixing in biopharmaceutical product/process development and manufacturing.
Mobius® Power MIX 500 is a 500 liter high performance, single-use mixing system targeted for mixing in biopharmaceutical product/process development and manufacturing.
Mobius® Power MIX 1000 is a 1000 liter high performance, single-use mixing system targeted for clinical scale mixing in biopharmaceutical product/ process development and manufacturing.
Mobius® Power MIX 2000 liter high performance, single-use mixing system meets the increasing demands for single-use systems in GMP biopharmaceutical manufacturing.
Biopharmaceutical companies are increasingly making the change from stainless steel systems to disposable technologies.
This study develops optimal process conditions for mixing and filtering of 1X PBS buffer using the 50 L, 200 L, and 1000 L Mobius® Single-Use Mixing Solution, Durapore® and Millipore Express® filters.
The Mobius® Single-use Mixing Solution delivers advanced technology for mixing pharmaceutical ingredients from intermediate to final drug products and for the preparation of process solutions, such as buffers and media.
The need for faster cycle times and higher levels of operational flexibility has accelerated the adoption of single-use processing solutions in the biopharmaceutical industry.
Cell culture media is typically mixed in bulk and aseptically transferred to the bioreactor
Antibody Drug Conjugates (ADCs) are a class of biomolecules that has seen rapid growth as an oncology therapeutic.
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