Home Products Pharma & Biopharma Manufacturing Sterile Filtration and Bioburden ControlPrefilters & Bioburden Control

Prefilters & Bioburden Control

Prefilters are a cost-effective, proven technology used throughout bioprocessing, providing flexibility for biopharma manufacturers by removing particulate impurities. They increase the capacity of high-performance sterilizing filters and protect costly chromatography columns. Our membrane-based prefilters can be used on a stand-alone basis for bioburden reduction in non-critical operations.

Our prefilters are available with different base media and a variety of membrane pore sizes. All are fully scalable from small-scale tools to pilot and production scale manufacturing. Most are offered as cartridge filters as well as disposable filters (single-use capsules). These industry-leading products and services are supported by decades of technical expertise, so you can be confident of success.

Milligard^® PES filters contain polyethersulfone (PES) membrane, are available in multiple pore sizes, and provide fast flow, high throughput, reliable particle removal and bioburden reduction claims. These filters are available in formats that can be sterilized by gamma-irradiation.

Milligard^® filters are constructed from mixed esters of cellulose on a polyester web and are available in multiple pore sizes. These provide high particle capacity and retention upstream of sterile filters.

PolySep™ II filters are mixed media filters that combine the high capacity of a depth filter and retention efficiency of a membrane in a single device, making them ideal for removing particles from plugging, viscous, and challenging streams.

Durapore^® 0.45 µm filters contain a polyvinylidene fluoride (PVDF) membrane that provides particulate removal and bioburden reduction. These filters are also available with an integrated 0.5 µm prefilter.

Regulatory Compliance

Milligard^® PES filters are supported by the Emprove^® Program which consolidates comprehensive product-specific testing data, quality statements, and regulatory information in a readily available format to simplify your compliance needs.

Related Product Resources

Products

capsule filters (214)

cartridge filters (72)

Opticap^® (41)

Polysep^™ (41)

Opticap^® XL 5 (40)

Milligard^® (31)

Opticap^® XL 10 (28)

Opticap^® XL 2 (25)

mixed cellulose esters (MCE) (214)

borosilicate glass fiber (BGF) (128)

polyethersulfone (71)

Sort by Relevance

Showing 1-20 of 286

Page 1 of 15

Showing 1-20 of 286

Compare

Product Number

Product Name

Product Description

Pricing

CGW673S03

Polysep^™ II 1.0/0.5 µm nominal, Cartridge

pore size 1.0/0.5 μm, cartridge nominal length 30 in. (75 cm)

CWSC02S03

Milligard^® 1.2/0.5 µm nominal, Cartridge

pore size 1.2/0.5 μm, cartridge nominal length 20 in. (50 cm), Code 0 (2-222; O-rings)

CGW671S03

Polysep^™ II 1.0/0.5 µm nominal, Cartridge

pore size 1.0/0.5 μm, cartridge nominal length 10 in. (25 cm)

CGW6M4S03

Polysep^™ II 1.0/0.5 µm nominal, Cartridge

pore size 1.0/0.5 μm, cartridge nominal length 4 in. (10 cm), Code M (2-118; O-rings)

CWSS01S03

Milligard^® 0.5/0.2 µm nominal, Cartridge

pore size 0.5/0.2 μm, cartridge nominal length 10 in. (25 cm), Code 0 (2-222; O-rings)

CGW3M4S03

Polysep^™ II 1.0/0.2 µm nominal, Cartridge

pore size 1.0/0.2 μm, cartridge nominal length 4 in. (10 cm), Code M (2-118; O-rings)

CMP271TS1

Milligard^® PES 1.2/0.2 µm nominal, Cartridge

pore size 1.2/0.2 μm, cartridge nominal length 10 in. (25 cm)

KMP2G003FF1

Milligard^® PES 1.2/0.2 μm nominal, Opticap^® Small Scale 300 Capsule

Fittings 3/4 in. Sanitary Flange Inlet and Outlet, Method Gamma-compatible or Autoclavable

KMP4G2STT1

Milligard^® PES 1.2/0.45 μm, Opticap^® T-line 20 capsule

inlet and outlet for 1.5 in. (Sanitary Flange ), sterilization compatible with autoclavable

SGW3A47HH3

Polysep^™ II 1.0/0.2 µm nominal, OptiScale^® Capsule

filtration area 17.7 cm², OptiScale^® 47, pore size 1.0/0.2 μm

KMP4G003HH1

Milligard^® PES 1.2/0.45 μm, Opticap^® Small Scale 300 Capsule

Fittings 9/16 in. Hose Barb Inlet and Outlet, Method Gamma-compatible or Autoclavable

KMP2G10TT1

Milligard^® PES 1.2/0.2 µm nominal, Opticap^® XL Capsule

inlet connection diam. 1.5 in., Opticap^® XL 10, pore size 1.2/0.2 μm

KMP2G05TT1

Milligard^® PES 1.2/0.2 µm nominal, Opticap^® XL Capsule

Opticap^® XL 5, inlet connection diam. 1.5 in., pore size 1.2/0.2 μm

KGW3A05FF1

Polysep^™ II 1.0/0.2 µm nominal, Opticap^® XL Capsule

Opticap^® XL 5, inlet connection diam. 3/4 in., pore size 1.0/0.2 μm, cartridge nominal length 5 in. (12.5 cm)

SMP2A25NB6

Milligard^® PES 1.2/0.2 µm nominal, OptiScale^® Capsule

filtration area 3.5 cm², OptiScale^® 25, pore size 1.2/0.2 μm

KWLCA05HH1

Milligard^® LPB 1.2/0.5 µm nominal, Opticap^® XL Capsule

Opticap^® XL 5, inlet connection diam. 9/16 in., pore size 1.2/0.5 μm, cartridge nominal length 5 in. (12.5 cm)

KMP4G05TH1

Milligard^® PES 1.2/0.45 µm, Opticap^® XL Capsule

Opticap^® XL 5

KGW3A02HH3

Polysep^™ II 1.0/0.2 µm nominal, Opticap^® XL Capsule

Opticap^® XL 2, inlet connection diam. 9/16 in., pore size 1.0/0.2 μm, cartridge nominal length 2 in. (5 cm)

SMP8A25NB6

Milligard^® PES 1.2/0.8 µm, OptiScale^® Capsule

filtration area 3.5 cm², OptiScale^® 25, pore size 1.2/0.8 μm

SWSCA47HH3

Milligard^® 1.2/0.5 µm nominal, OptiScale^® Capsule

filtration area 17.7 cm², OptiScale^® 47, pore size 1.2/0.5 μm

Page 1 of 15

Related Product Categories

Buffer Filtration

There are multiple options for buffer filtration in biomanufacturing. Filter selection is based on process biosafety needs, buffer throughput and economics. Filters for processing buffers in biomanufacturing provide bioburden control, sterilizing-grade or virus retention performance.

Filter Housings

Discover customizable Series 4000™ stainless steel filter housings for precise biopharmaceutical processes.

Sterile Filters

Secure microbial safety with sterile filtration and disposable filters. Choose the right sterilizing filter for effective bioburden control.

Clarification Prefilters

Elevate pharma process purity with efficient clarification prefilters. Safeguard downstream operations from impurities.

Final Sterile Filtration & Filling

Enhance final filtration and sterile fill processes with pre-sterilized, single-use systems for optimized operations.

Related Applications

Monoclonal Antibody Manufacturing

Monoclonal antibody manufacturing is a highly templated approach used to produce mAb-based immunotherapies. Robust, scalable process solutions are required at every step to ensure high therapeutic concentration and process safety, while meeting speed-to-market and cost containment concerns.

Blood Plasma Fractionation

Consistent, reliable performance is key to blood plasma fractionation, posing challenges to improve yield, maintain process economics, and manage regulatory requirements. Learn how the right partner can help fractionators to better serve patients globally with enhanced IgG, albumin, and Factor VIII products.

Classical Pharmaceutical Formulation & Manufacturing

Manufacturing the final dosage form of a small molecule drug requires robust quality and design in development of the formulation and production of the final product. Explore solutions and best practices to advance and accelerate small molecule pharmaceuticals, from development to commercialization.

Gene Therapy Manufacturing

Growing use of gene therapies is driving rapid innovation in an evolving global market. Manufacturers bringing new gene therapies to life face complex challenges, requiring an experienced partner capable of integrating vector manufacturing, testing, safety, process development, and regulatory compliance.

Vaccine Manufacturing

From early phase development, through downstream purification to large scale vaccine production: learn more about vaccine process development and application expertise.

Pharma & Biopharma Startup Hub

Your new molecule or therapy begins its journey here. Find solutions and resources to navigate your path to successful drug discovery, development, and commercialization.

Related Services

Emprove^® Program

Emprove^® Program: The smart way to master compliance and control. Complementing our product portfolio, the Emprove^® Program provides convenient access to reliable technical, regulatory and supply information in Emprove^® Dossiers to support your risk assessment continuum.

Training & Education

Pharmaceutical and biopharmaceutical manufacturers can enhance their skill sets with practical, hands-on training courses in-person or streamed live from our M Lab™ Collaboration Centers.

Maintenance & Service Plans

Browse our maintenance and service plans for Milli-Q water purification systems and our microbiology testing systems.

Monoclonal Antibody Manufacturing