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Vaccine Manufacturing
From early phase development, through downstream purification to large scale vaccine production: learn more about vaccine process development and application expertise.
Manufacturing Strategies for mRNA Vaccines and Therapeutics
mRNA technology offers therapeutic versatility; its delivery systems induce protein production for various applications.
mRNA 疫苗和疗法的生产策略
mRNA 技术具有多种治疗功能；其输送系统可诱导蛋白质的产生，从而实现各种应用。
疫苗生产_生物制药生产-默克生命科学
疫苗是针对病原体和其他传染病的最具成本效益的卫生干预措施之一，每年可挽救数百万人的生命，同时改善无数其他人的生活质量。
Coronavirus (SARS-CoV-2) Viral Proteins
SARS-CoV-2 structural proteins: envelope (E), membrane (M), nucleocapsid (N), spike (S). Explore related reagents for research.
病毒疫苗生产
通过合作进行量身定制的病毒疫苗生产，应对病毒特有的挑战。
mRNA 疫苗和疗法制造
mRNA 疫苗技术可为疾病预防提供快速开发和规模化生产。
质粒DNA疫苗生产
了解如何克服 pDNA 疫苗生产过程中的难题，包括生产率低和分离问题。
蛋白亚单位疫苗生产
本页面介绍了蛋白亚单位疫苗的概况，这种疫苗掺入了来自病毒病原体的重组蛋白质片段。具体包括亚单位疫苗生产工作流程，以及确保成功生产必需的产品和技术。
蛋白亚单位疫苗生产
本页面介绍了蛋白亚单位疫苗的概况，这种疫苗掺入了来自病毒病原体的重组蛋白质片段。具体包括亚单位疫苗生产工作流程，以及确保成功生产必需的产品和技术。
病毒样颗粒(VLP)疫苗制造
VLP疫苗制造商必须通过可靠的放大来优化上游的生产力、通过稳健的杂质去除实现产量和效率目标、尽可能提高下游回收率并确保患者安全。Merck整合的产品组合、监管及应用专家知识可帮助可靠应对这些工艺挑战。
病毒载体疫苗制造
通过模板化工艺生产活载体疫苗。挑战：产量损失、过滤、聚集、放大。合作克服制造障碍。
默克&中检院携手标准物质研讨会 共迎2022世界标准日
10月14日是世界标准日。中检院与默克共同举办2022年世界标准日标准物质线上研讨会
Membrane Filtration: Efficient Particle Retention and Bioburden Reduction in Bioprocessing Fluid Streams
Some prefilters reduce bioburden and can be used as a cost-effective alternative to sterilizing filters for bioburden control in bioprocessing.
Cell Harvest, Lysis, Neutralization and Clarification of Plasmid DNA (pDNA) for mRNA, plasmid-based DNA Vaccines, and Viral Vector applications
An overview of the cell harvest, lysis, neutralization, and clarification steps used for pDNA purification along with case study and practical advice.
Plasmid DNA Purification Process
Free eBook outlines plasmid DNA manufacturing process and downstream purification challenges for various applications.
Cost Modeling Vaccine Manufacturing: Estimate Production Costs for mRNA and other Vaccine Modalities
A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.
Egg-based and Cell-based Influenza Vaccine Manufacturing Methods
Influenza vaccines are commonly made using egg-based and cell-based manufacturing strategies. Find step-by-step information on the manufacturing process for each method.
Eshmuno® Fit Custom Affinity Resin Development Services: Frequently Asked Questions
This page answers all the frequently asked questions related to our Eshmuno® Fit custom affinity resin development services.
Formulation Strategies for mRNA Vaccines and Therapeutics
Discover efficient strategies for formulating mRNA, including information on lipid selection, lipid nanoparticles, and excipients for optimal stability.
mRNA Synthesis for the Development of Vaccines and Therapeutics
Understand how mRNA vaccines induce immunity. and read how synthetic mRNA is prepared for vaccine immunogens and other biopharmaceuticals. Find reagents for synthesis of mRNA.
Virus-like Particle (VLP) Vaccine Bioprocessing and Formulation Steps
This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.
Bioprocessing Summit
Vaccine processing evolution focuses on agile manufacturing solutions amid the COVID pandemic.
BIO International
We warmly invite you to visit booth 4735 at BIO International and connect with the MilliporeSigma team.
Platform Technologies to Accelerate Novel Vaccine Development and Manufacturing
In this webinar, we present a comparison of novel technologies, discuss key considerations for manufacturing, and share selected case studies for platforms such as virus-like-particles, viral vectors, plasmid DNA, and mRNA platforms.
Personalized T cell therapy for HBV and HCC
This webinar explores challenges and strategies in T cell engineering for promising cancer immunotherapy options.
A Sensitive Method to Quantify HIV-1 Antibody in Mucosal Samples
A Sensitive Method to Quantify HIV-1 Antibody in Mucosal Samples
Virus-Based Vaccine Manufacturing
Tailored viral vaccine manufacturing addresses virus-specific challenges through collaboration.
mRNA Vaccines and Therapeutics Manufacturing
mRNA vaccine technology offers rapid development and scalable manufacturing for disease prevention.
Plasmid DNA Vaccines Manufacturing
Learn about overcoming challenges in manufacturing pDNA vaccines, including low productivity and separation issues.
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