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Calibration, qualification, and validation
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Determination of Stevioside and Rebaudioside A in Stevia leaves, beverages and food additives using HPTLC-MS
HPTLC-MS was used to analyze stevioside and rebaudioside in artificial sweeteners, stevia plants, cola and isotonic drinks with a minimum of sample preparation.
The Proper Storage and Handling of Volatile Analytical Standards
Properly storing and handling standards is critical to achieving accurate and reproducible analytical results.
Columns and Analytical Standards for Protein SEC
Size-exclusion chromatography (SEC) columns and ready-to-use standards facilitate method development and increase robustness of protein SEC methods.
Traceable Organic Certified Reference Materials for P-31 qNMR
The use of CRMs for the NMR quantification of phosphorylated organic compounds and metabolites offers several advantages as it is based on a signal comparison of the analyte with an internal or external reference standard.
Quantification of Infliximab in Human Serum by LC-MS/MS Using A Full-Length Stable Isotope Labeled Internal Standard
Infliximab, a chimeric monoclonal antibody, is used to treat rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and other autoimmune diseases.
Synthetic Cannabinoid Analysis
A large variety of cannabinoid drug standards, along with an HPLC method with the Supelco Ascentis® Express RP-Amide column, are presented in this article.
NMR Reference Standards
NMR reference standards ensure proper instrument performance. Review key operational parameters for these standards such as pw90, sensitivity, resolution and line shape.
Certified Reference Materials for ¹⁹F Quantitative NMR Ensuring Traceability to “The International System of Units” (SI)
In certain cases, 1H qNMR reaches its limits, especially regarding the certification of complex and larger molecules. However, new fields of application often also bring along the presence of heteroatoms, namely 31P and 19F. We therefore introduced 3 CRMs for
HPLC Separation of Ginsenosides from American Ginseng
The HPLC method for ginsenoside separation was optimized using a ginsenoside standard mixture and then applied to a sample of American Ginseng root. The experimental conditions and chromatograms are shown.
Improving the Current USP Method for the Analysis of Lansoprazole Drug Substance Using HPLC Columns Based on Fused-Core® Particle Technology
Compendial methods from the USP (United States Pharmacopeia) are widely used in pharmaceutical drug product and raw materials testing. However, not all methods in the USP use modern technologies. In chromatographic methods, it is not uncommon that older brands of
SPME in the Analysis of Illicit Drugs
SPME is used in the analysis of amphetamine compounds by doing pre-extraction derivatization, and is also used in general determinations of other drugs of abuse.
Chiral and Achiral LC-MS Analysis of Warfarin™ in Plasma Samples
Clinical laboratories are beginning to reap the benefits of LC-MS in terms of its sensitivity, specificity, throughput, and potential to reduce cost per sample. The purpose of this study was to demonstrate the LC-MS analysis of Warfarin in plasma samples
Radiello Diffusive Sampler for Monitoring 1,3-Butadiene and Isoprene in Workplace Air
The manufacturing of elastomers makes wide use of 1,3-butadiene (CAS No. 106-99-0) and isoprene (2-methyl- 1,3-butadiene, CAS No. 78-79-5). Both compounds are classifi ed as carcinogenic by the International Agency for Research on Cancer (IARC). 1,3-Butadiene is currently listed in
Isotopic Labeling for NMR Spectroscopy of Biological Solids
Isotopic Labeling for NMR Spectroscopy of Biological Solids;
Extractables Study with LC-UV/MS
Reliable identification and quantification of unknown extractables of a single-use system (SUS) with a 21 component CRM mix for liquid chromatography (LC-UV/MS) methods using Ascentis® C18 column.
Titripac® Sustainable Packaging for Ready-to-Use Certipur® pH Buffers
Learn about our ready-to-Use Certipur® pH Buffer solutions (4 L & 10 L), available in an innovative Titripac® sustainable packaging for a wide pH range of 1 to 12.
Extractables Studies of Single-Use Equipment Immediate Identification and Quantification of Unknown Extractables by GC/MS with a Certified Reference Material Mix for Extractables and Leachables
Identification and quantification of the most common extractables originating from single-use equipment by GC/MS and an Extractables and Leachables Screening Standard.
Biodiesel
Learn more about Biodiesel as a renewable, alternative diesel fuel produced from vegetable oils, animal fats, or recycled restaurant grease.
Drinking Water Testing by Ion Chromatography using Ultrapure Water
This study reviews the suitability of ultrapure water for the IC analysis of drinking water. Inorganic ions and disinfectant by-products (DBPs) were assessed.
Importance of Volumetric Solution Standardization
The titer determination or standardization of a titration solution is essential for accurate and reliable titration results.
Complete Workflow for the Analysis of California List of Pesticides in Cannabis by LC-MS/MS and GC-MS/MS
To show product safety, it is mandatory to test cannabis flowers for the presence of pesticides. In this article, we show a complete workflow for sample preparation and analysis of cannabis for the pesticides registered in California, by LC-MS/MS and
Optimizing for High Throughput Analysis of Cannabinoids in a Variety of Matrices Using Ascentis® Express C18 Column
A complete workflow for the HPLC separation of 17 cannabinoids in different cannabis products using Ascentis® Express C18 Column in a shorter run time with retention time stability. Learn more here.
NMR Deuterated Solvent Properties Reference Chart
Use this reference table to find the coupling values and chemical shifts of our NMR (deuterated) solvents. Melting and boiling points, molecular weight, density, and CAS number are also listed.
Flame Retardant Analytical Standards
Flame Retardant Standards: PBDE Standards. Polybrominated diphenyl ether standards accompany our chromatography products for this important analysis.
Biomolecular NMR: Isotope Labeling Methods for Protein Dynamics Studies
We presents an informational article concerning biomolecular NMR and the use of Isotope Labeling Methods for Protein Dynamics Studies.
How to Choose the Correct Reference Material Quality Grade
Reference materials, standards and certified reference materials are critical for analytical testing. We can help you to choose the ideal reference material for your application, whether you are using reference materials for calibration or quantitative analysis.
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
An LC/MS Peptide Standard for Rapid System Suitability Assessment and Retention Time Translation Across LC/MS Platforms
Standards are critical in liquid chromatography/mass spectrometry (LC/MS) based proteomics to ensure optimal and consistent system performance before, during, and after sample analysis.
Melamine Analysis via GC-MS
Sigma-Aldrich presents an article about the analysis of melamine and related compounds in dog food with the use of more economical gas chromatography-mass spectrometry (GC-MS) instrumentation.
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