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Resonance Raman scattering of catalytic beacons for DNA detection.

Chemical communications (Cambridge, England) (2013-03-15)
Kristy S McKeating, Duncan Graham, Karen Faulds
PMID23486766
ABSTRACT

A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.

MATERIALS
Product Number
Brand
Product Description
09743
Supelco
3,3′,5,5′-Tetramethylbenzidine, standard for GC
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3,3′,5,5′-Tetramethylbenzidine, tablet, 1 mg substrate per tablet
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