CN
- Development of a "signal-on" electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection.
Development of a "signal-on" electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection.
Chemical communications (Cambridge, England) (2013-03-19)
Yao Wu, Rebecca Y Lai
PMID23503676
ABSTRACT
We report a reagentless and reusable "signal-on" electrochemical DNA sensor that utilizes oligo-thymine as a flexible spacer. This sensor design is sensitive, specific, and selective; it is potentially generalizable for detection of a wide range of biomedical-relevant nucleic acid sequences.
MATERIALS
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Sigma-Aldrich
Methylene Blue solution, for microscopy, concentrate according to Ehrlich, concentrated, aqueous solution