Skip to Content

CN

Methanol and ethylene glycol intoxication.

Methanol and ethylene glycol intoxication.

Critical care clinics (2012-09-25)

James A Kruse

ABSTRACT

Accidental or intentional ingestion of substances containing methanol and ethylene glycol can result in death, and some survivors are left with blindness, renal dysfunction, and chronic brain injury. However, even in large ingestions, a favorable outcome is possible if the patient arrives at the hospital early enough and the poisoning is identified and appropriately treated in a timely manner. This review covers the common circumstances of exposure, the involved toxic mechanisms, and the clinical manifestations, laboratory findings, and treatment of methanol and ethylene glycol intoxication.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Ethylene glycol, anhydrous, 99.8%

Sigma-Aldrich

Methanol, anhydrous, 99.8%

Sigma-Aldrich

Ethylene glycol, BioUltra, ≥99.5% (GC)

Supelco

Methanol, analytical standard

Supelco

Ethylene glycol solution, suitable for NMR (reference standard), 80% in DMSO-d₆ (99.9 atom % D), NMR tube size 5 mm × 8 in.

Sigma-Aldrich

Methanol, suitable for NMR (reference standard)

Supelco

Ethylene glycol, Pharmaceutical Secondary Standard; Certified Reference Material

Sigma-Aldrich

Methanol, purification grade, 99.8%

USP

Ethylene glycol, United States Pharmacopeia (USP) Reference Standard

Supelco

Ethylene glycol, analytical standard

Supelco

Methanol, Pharmaceutical Secondary Standard; Certified Reference Material

Sigma-Aldrich

Methanol, ACS reagent, ≥99.8%

Sigma-Aldrich

Methanol, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8% (GC)

Sigma-Aldrich

Ethylene glycol, Vetec^™, reagent grade, 98%

Sigma-Aldrich

Methanol, puriss., meets analytical specification of Ph Eur, ≥99.7% (GC)

Sigma-Aldrich

Methanol, BioReagent, ≥99.93%

Sigma-Aldrich

Methanol, suitable for HPLC, ≥99.9%

Sigma-Aldrich

Methanol, suitable for HPLC, gradient grade, ≥99.9%

Sigma-Aldrich

Methanol, HPLC Plus, ≥99.9%

Sigma-Aldrich

Methanol, suitable for HPLC, gradient grade, suitable as ACS-grade LC reagent, ≥99.9%

Sigma-Aldrich

Methanol, ACS reagent, ≥99.8%

Sigma-Aldrich

Ethylene glycol, ReagentPlus^®, ≥99%

Sigma-Aldrich

Methanol, ACS reagent, ≥99.8%

Sigma-Aldrich

Methanol, ACS spectrophotometric grade, ≥99.9%

Sigma-Aldrich

Ethylene glycol, spectrophotometric grade, ≥99%

Sigma-Aldrich

Methanol, Laboratory Reagent, ≥99.6%

Sigma-Aldrich

Methanol solution, (Methanol:Dimethyl sulfoxide 1:1 (v/v))

Sigma-Aldrich

Ethylene glycol 5 M solution

Sigma-Aldrich

Methanol solution, contains 0.50 % (v/v) triethylamine

Sigma-Aldrich

Methanol solution, suitable for NMR (reference standard), 4% in methanol-d₄ (99.8 atom % D), NMR tube size 3 mm × 8 in.