HPLC Analysis of Metalaxyl Enantiomers on Astec® Cellulose DMP
Materials
related product
used together
Product No.
Description
Pricing
CONDITIONS
column
Astec Cellulose DMP, 25 cm x 4.6 mm I.D., 5 μm particles (51099AST)
mobile phase
[A] ethanol; [B] hexane, (25:75, A:B)
flow rate
1.0 mL/min
pressure
740 psi (51 bar)
column temp.
25 °C
detector
UV, 220 nm
injection
10 μL
sample
1 mg/mL in ethanol
Description
Analysis Note
Metalaxyl is a 1:1 mixture of (R)- and (S)-2-[(2,6-dimethylphenyl)methoxyacetylamino]propionic acid methyl ester. Both enantiomers are fungicides used in agriculture, horticulture, and forestry. They act by inhibiting mycelial growth and spore formation. Metalaxyl-M is the biologically active (R)-enantiomer. Technical-grade metalaxyl-M consists of a minimum of 97% of the (R)-enantiomer and 3% of the (S)-enantiomer. Chiral LC on Astec Cellulose DMP was used to separate the two enantiomers.
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany