CN

89231

Sigma-Aldrich

(-)-α-侧柏酮

≥96.0% (GC)

别名:
(1S,4R)-1-异丙基-4-甲基双环[3.1.0]己-3-酮
Empirical Formula (Hill Notation):
C10H16O
分子量:
152.23
Beilstein/REAXYS Number:
4660369
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

测定

≥96.0% (GC)

旋光性

[α]20/D −19.0±2.0°, neat

折射率

n20/D 1.450

密度

0.914 g/mL at 20 °C (lit.)

储存温度

2-8°C

SMILES string

CC(C)[C@@]12C[C@@H]1[C@@H](C)C(=O)C2

InChI

1S/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3/t7-,8-,10+/m1/s1

InChI key

USMNOWBWPHYOEA-MRTMQBJTSA-N

正在寻找类似产品? Visit 产品对比指南

一般描述

Thuja occidentalis 的精油中发现的单萜酮 (-)-α-Thujone 显示出强效的抗肿瘤作用。

包装

1, 5 mL in glass bottle

生化/生理作用

GABAA 受体拮抗剂。

其他说明

手性结构单元

象形图

Exclamation mark

警示用语:

Warning

危险声明

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

RIDADR

NA 1993 / PGIII

WGK Germany

WGK 1

闪点(F)

147.2 °F - closed cup

闪点(C)

64 °C - closed cup

分析证书

原产地证书 (CofO)

Hakam Alkhateeb et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 36(3), 361-367 (2011-05-18)
Rescue of palmitate-induced insulin resistance has been linked with improvements in fatty acid oxidation, but importantly, not always with concurrently altered AMPK or ACC2 phosphorylation. Therefore, we examined the interrelationships among AMPK, ACC2, and fatty acid oxidation under 12 controlled...
Nour W Al-Haj Baddar et al.
Natural product research, 25(12), 1180-1184 (2011-07-12)
Thujone, which is the major constituent in Salvia sp. (Lamiaceae), was found to correct the lipid profile (cholesterol and triglycerides) in diabetic rats. Oral treatment with thujone (5 mg kg⁻¹ body weight dose) significantly adjusted cholesterol and triglyceride levels in...
Ilioara Oniga et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 114(2), 593-595 (2010-08-13)
The quantitative and qualitative analysis of essential oils obtained from Salvia officinalis L. (Lamiaceae) cultivated in Romania is reported in this paper. The essential oils were obtained from fresh and dried material harvested from plants cultivated in Cluj (Romania) and...
Marcin Szczot et al.
Journal of natural products, 75(4), 622-629 (2012-03-01)
α-Thujone (1a), a constituent of wormwood, has been suspected to cause adverse psychoactive reactions in addicted drinkers of absinthe. While the content of 1a in absinthe is too low for such effects, at higher doses it can indeed induce seizures...
Adebola O Oyedeji et al.
Natural product communications, 4(6), 849-852 (2009-07-29)
Safety of Artemisia afar has been a controversial issue due to its high thujone content. Despite the declaration of the World Health Organization in the 1970s of the plant being unsafe for consumption, it is still commonly used in folklore...

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

WeChat Icon
Bilibili Icon

默克

研究、开发、生产

作为生命科学行业的全球领先供应商,我们致力于为研究、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. 保留所有权利。

严格禁止在未经同意的情况下转载本网站之所有信息。 Sigma-Aldrich品牌产品均由Sigma-Aldrich LLC.独家贩售。