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Merck
CN

177504

十六烷二酸

96%

别名:

塔普酸

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关于此项目

线性分子式:
HOOC(CH2)14COOH
化学文摘社编号:
分子量:
286.41
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
208-013-5
Beilstein/REAXYS Number:
1792831
MDL number:
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Quality Level

assay

96%

mp

120-123 °C (lit.)

SMILES string

OC(=O)CCCCCCCCCCCCCCC(O)=O

InChI

1S/C16H30O4/c17-15(18)13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(19)20/h1-14H2,(H,17,18)(H,19,20)

InChI key

QQHJDPROMQRDLA-UHFFFAOYSA-N

General description

十六烷二酸(HDDA),又称它普酸,是直链的脂肪二羧酸,分子式C₁₆H30O₄。其饱和烃链的两端有两个羧酸基(-COOH),赋予聚合物热稳定性、疏水性和生物相容性。

Application

十六烷二酸可用于:
  • 作为心脏代谢成像的示踪剂(镓-68放射性标记),在心脏PET扫描中可视化脂肪酸代谢。它的生物相容性和天然脂肪酸途径模拟,可增强对心脏功能的诊断评估能力。
  • 作为前体,经由熔融缩聚反应制备非交联三元共聚酯。所得材料可用于制作环保型食品包装材料。


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Vukic Soskic et al.
Journal of proteome research, 5(12), 3453-3458 (2006-12-02)
Serum and plasma are the major sources of human material for clinical molecular diagnostics and drug discovery. However, due to the high abundance of some proteins, of which serum albumin (SA) is most prominent, lower-abundance proteins often remain undetectable in
J E Pettersen et al.
Journal of lipid research, 15(6), 551-556 (1974-11-01)
The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 micro mole/min/g wet wt of tissue, about 10% of that for
N Shirane et al.
Biochemistry, 32(49), 13732-13741 (1993-12-14)
Cytochrome P450BM-3 preferentially oxidized fatty acids with terminal double or triple bonds to the omega-2 hydroxylated fatty acids rather than, respectively, to the epoxide or diacid metabolites. The enzyme is inactivated during catalytic turnover of long, terminally unsaturated fatty acids



全球贸易项目编号

货号GTIN
177504-1G04061826661635
177504-5G04061838753250