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Merck
CN

223867

2,6-二异氰酸甲苯酯

97%

别名:

2-甲基-间亚苯基二异氰酸酯

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关于此项目

线性分子式:
CH3C6H3(NCO)2
化学文摘社编号:
分子量:
174.16
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
202-039-0
Beilstein/REAXYS Number:
2211546
MDL number:
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产品名称

2,6-二异氰酸甲苯酯, 97%

InChI key

RUELTTOHQODFPA-UHFFFAOYSA-N

InChI

1S/C9H6N2O2/c1-7-8(10-5-12)3-2-4-9(7)11-6-13/h2-4H,1H3

SMILES string

Cc1c(cccc1N=C=O)N=C=O

assay

97%

form

liquid

autoignition temp.

>1148 °F

refractive index

n20/D 1.571 (lit.)

bp

129-133 °C/18 mmHg (lit.)

density

1.225 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Carl Johan Sennbro et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 8(3-4), 204-217 (2003-08-29)
Occupational exposure to diisocyanates within the plastic industry causes irritation and disorders in the airway. The aim of this study was to develop, validate and characterize a method for the determination of 2,4-toluenediamine (2,4-TDA), 2,6-toluenediamine (2,6-TDA), 1,5-diaminonaphthalene (1,5-NDA) and 4,4'-methylenedianiline
P Lind et al.
The Analyst, 122(2), 151-154 (1997-02-01)
Desalted plasma from a 2,4- and 2,6-toluene diisocyanate (2,4- and 2,6-TDI) exposed worker at a factory producing flexible polyurethane foam was separated and fractionated into 200 fractions using ion-exchange chromatography followed by a gel-filtration separation and fractionation into 59 fractions.
Y Sugawara et al.
International archives of allergy and immunology, 101(1), 95-101 (1993-01-01)
Guinea pigs were sensitized with 2,4-toluene diisocyanate (TDI) by a repetitive application onto the bilateral nasal vestibules once a day for 5 consecutive days. When these animals were further treated with TDI for additional 9 weeks, a number of these
B W Day et al.
Chemical research in toxicology, 10(4), 424-431 (1997-04-01)
During our ongoing studies of the reactions of toluene diisocyanate (2,4- and 2,6-diisocyanatotoluene, TDI) in vivo, it became apparent that reactive form(s) of these diisocyanates reach(es) the circulatory system after passage through the respiratory system. Based on recent work by
J Huang et al.
Archives of toxicology, 67(6), 373-378 (1993-01-01)
Groups of guinea pigs were exposed via inhalation to toluene diisocyanate (TDI) ranging from 0.02 to 1.0 ppm for 3 h/day on 5 consecutive days. Three weeks later, guinea pigs were challenged with TDI-GSA conjugates. Evaluations were based on TDI

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