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Merck
CN

281255

Sigma-Aldrich

1,4-二羟基-2-萘甲酸

97%

别名:

1,4-二羟基-2-萘甲酸, 1,4-二羟基-2-萘甲酸盐

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关于此项目

线性分子式:
(HO)2C10H5CO2H
化学文摘社编号:
分子量:
204.18
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案

97%

mp

220 °C (dec.) (lit.)

官能团

carboxylic acid

SMILES字符串

OC(=O)c1cc(O)c2ccccc2c1O

InChI

1S/C11H8O4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13H,(H,14,15)

InChI key

VOJUXHHACRXLTD-UHFFFAOYSA-N

一般描述

目前确知来自费氏丙酸杆菌的1,4--二羟基-2-萘甲酸可促进双歧杆菌增殖。这种产品在牛皮癣治疗中具有潜在的治疗应用

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R Bentley et al.
Journal of natural products, 46(1), 44-59 (1983-01-01)
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Escherichia coli is used as a model organism for elucidation of menaquinone biosynthesis, for which a hydrolytic step from 1,4-dihydroxy-2-naphthoyl-coenzyme A (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate is still unaccounted for. Recently, a hotdog fold thioesterase has been shown to catalyze this conversion
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Triple therapy with amoxicillin, clarithromycin, and a proton-pump inhibitor is a common therapeutic strategy for the eradication of Helicobacter pylori (H. pylori). However, frequent appearance of clarithromycin-resistant strains is a therapeutic challenge. While various quinones are known to specifically inhibit
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Bioscience, biotechnology, and biochemistry, 73(11), 2535-2537 (2009-11-10)
The incorporation of [1-(13)C]glucose into 2,3-epoxysesamone, the main prenylnaphthoquinone in a hairy root culture of Sesamum indicum, indicated that the naphthoquinone moiety and dimethylallyl group were respectively derived from o-succinylbenzoate produced through a shikimate pathway and non-mevalonate pathway. The labeling

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