281255
1,4-二羟基-2-萘甲酸
97%
别名:
1,4-二羟基-2-萘甲酸, 1,4-二羟基-2-萘甲酸盐
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关于此项目
线性分子式:
(HO)2C10H5CO2H
化学文摘社编号:
分子量:
204.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
250-674-7
MDL number:
产品名称
1,4-二羟基-2-萘甲酸, 97%
InChI key
VOJUXHHACRXLTD-UHFFFAOYSA-N
InChI
1S/C11H8O4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13H,(H,14,15)
SMILES string
OC(=O)c1cc(O)c2ccccc2c1O
assay
97%
mp
220 °C (dec.) (lit.)
functional group
carboxylic acid
Quality Level
General description
目前确知来自费氏丙酸杆菌的1,4--二羟基-2-萘甲酸可促进双歧杆菌增殖。这种产品在牛皮癣治疗中具有潜在的治疗应用。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D J Shaw et al.
Journal of bacteriology, 152(3), 1132-1137 (1982-12-01)
Four independent menaquinone (vitamin K(2))-deficient mutants of Escherichia coli, blocked in the conversion of o-succinylbenzoate (OSB) to 1,4-dihydroxy-2-naphthoate (DHNA), were found to represent two distinct classes. Enzymatic complementation was observed when a cell-free extract of one mutant was mixed with
V Sharma et al.
Gene, 168(1), 43-48 (1996-02-02)
In Escherichia coli, the biosynthesis of the electron carrier menaquinone (vitamin K2) involves at least seven identified enzymatic activities, five of which are encoded in the men cluster. One of these, the conversion of o-succinylbenzoic acid to 1,4-dihydroxy-2-naphthoic acid, requires
Y Saito et al.
Journal of biochemistry, 89(5), 1445-1452 (1981-05-01)
1,4-Dihydroxy-2-naphthoate:polyprenyltransferase was detected in the membrane fraction from Micrococcus luteus. The specificity of the enzyme ws so tolerant as regards the prenyl-donating substrate that prenyl pyrophosphates ranging in chain length from C15 to C45 were active as substrates. The monophosphate
Masayuki Uchida et al.
Regulatory toxicology and pharmacology : RTP, 60(2), 262-267 (2010-12-22)
Propionibacterium freudenreichii ET-3 (7025) culture, a cell-free product of whey fermentation by P. freudenreichii ET-3, has been shown to promote the growth of Bifidobacteria through the action of 1,4-dihydroxy-2-naphthoic acid (DHNA). Here we report the results of two clinical studies
Jincai Ma et al.
Environmental microbiology, 11(1), 149-158 (2008-09-25)
In this study, we investigated the role of menaquinone biosynthesis genes in selenate reduction by Enterobacter cloacae SLD1a-1 and Escherichia coli K12. A mini-Tn5 transposon mutant of E. cloacae SLD1a-1, designated as 4E6, was isolated that had lost the ability
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