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552224

2-氨基-5-氯苯酚

Name: 2-氨基-5-氯苯酚
Brand: ALDRICH

97%

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关于此项目

线性分子式:

H₂NC₆H₃(Cl)OH

化学文摘社编号:

28443-50-7

分子量:

143.57

NACRES:

NA.22

PubChem Substance ID:

24879253

UNSPSC Code:

12352100

EC Number:

249-020-3

MDL number:

MFCD02093863

Assay:

97%

Form:

solid

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属性

Quality Level

100

assay

97%

form

solid

mp

145-153 °C (lit.)

functional group

chloro

SMILES string

Nc1ccc(Cl)cc1O

InChI

1S/C6H6ClNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2

InChI key

FZCQMIRJCGWWCL-UHFFFAOYSA-N

说明

General description

2-Amino-5-chlorophenol can be synthesized from 2-chloro-5-nitrophenol via reduction. It can also be obtained from 1-chloro-4-nitrobenzene by using a bacterial strain LW1. 2-Amino-5-chlorophenol participates in the condensation reaction with acetylferrocene to afford ferrocenyl Schiff bases bearing a phenol group.

Application

2-Amino-5-chlorophenol may be used to synthesize 2-amino-5-chloromuconic semialdehyde and benzoxazole derivatives.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Initial reactions in the biodegradation of 1-chloro-4-nitrobenzene by a newly isolated bacterium, strain LW1.

E Katsivela et al.

Applied and environmental microbiology, 65(4), 1405-1412 (1999-04-02)

Bacterial strain LW1, which belongs to the family Comamonadaceae, utilizes 1-chloro-4-nitrobenzene (1C4NB) as a sole source of carbon, nitrogen, and energy. Suspensions of 1C4NB-grown cells removed 1C4NB from culture fluids, and there was a concomitant release of ammonia and chloride.

Characterization of genes involved in the initial reactions of 4-chloronitrobenzene degradation in Pseudomonas putida ZWL73.

Yi Xiao et al.

Applied microbiology and biotechnology, 73(1), 166-171 (2006-04-28)

The genes encoding enzymes involved in the initial reactions during degradation of 4-chloronitrobenzene (4CNB) were characterized from the 4CNB utilizer Pseudomonas putida ZWL73, in which a partial reductive pathway was adopted. A DNA fragment containing genes coding for chloronitrobenzene nitroreductase

2-Amino-5-chlorophenol toxicity in renal cortical slices from Fischer 344 rats: effect of antioxidants and sulfhydryl agents.

M Valentovic et al.

Toxicology and applied pharmacology, 161(1), 1-9 (1999-11-24)

2-Amino-5-chlorophenol is nephrotoxic through an unidentified mechanism. This study examined the in vitro toxicity of 2-amino-5-chlorophenol in renal cortical slices from Fischer 344 rats and specifically assessed induction of lipid peroxidation and depletion of renal glutathione. Renal cortical slices exposed

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货号	GTIN
552224-25G	04061832280264
552224-5G	04061832581866