D67200
2,3-二氯-1,4-萘醌
98%
别名:
二氯萘醌
方案
98%
表单
powder
mp
194-197 °C (lit.)
SMILES字符串
ClC1=C(Cl)C(=O)c2ccccc2C1=O
InChI
1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H
InChI key
SVPKNMBRVBMTLB-UHFFFAOYSA-N
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警示用语:
Danger
危险分类
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
农药列管产品
危险化学品
C A Pritsos et al.
Biochemical pharmacology, 35(7), 1131-1135 (1986-04-01)
Dietary exposure of rats to a high concentration of 2,3-dichloro-1,4-naphthoquinone (CNQ) (2 g/kg diet) for 60 days altered cardiac mitochondrial function and activities of anti-oxidant enzymes in hepatic and cardiac tissue. CNQ moderately depressed the cardiac mitochondrial respiratory control ratio
Ibrahim A Darwish
Journal of AOAC International, 88(1), 38-45 (2005-03-12)
Three simple and sensitive spectrophotometric methods were developed and validated for determination of the hydrochloride salts of fluoxetine, sertraline, and paroxetine in their pharmaceutical dosage forms. These methods were based on the reaction of the N-alkylvinylamine formed from the interaction
C A Pritsos et al.
Biochemical pharmacology, 33(23), 3771-3777 (1984-12-01)
The addition of 2,3-dichloro-1,4-naphthoquinone (CNQ) to substrate-depleted, GSH-supplemented rat liver mitochondria resulted in a dose-dependent depletion of reactable suflhydryl groups and a concomitant increase in mitochondrial disulfide content at a ratio of 2 thiols depleted/disulfide generated. The molar ratio of
C A Pritsos et al.
Research communications in chemical pathology and pharmacology, 42(2), 271-280 (1983-11-01)
The addition of 2,3-dichloro-1,4-naphthoquinone (CNQ) to isolated mitochondria supplemented with GSSG resulted in a respiratory burst with the production of O2- and H2O2, and a decrease in the level of measurable disulfide. Superoxide generated by the xanthine oxidase system or
Christophe Morisseau et al.
Environmental health perspectives, 117(12), 1867-1872 (2010-01-06)
Legislation at state, federal, and international levels is requiring rapid evaluation of the toxicity of numerous chemicals. Whole-animal toxicologic studies cannot yield the necessary throughput in a cost-effective fashion, leading to a critical need for a faster and more cost-effective
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