W327204
2,5-二甲基吡嗪
≥98%, FG
别名:
Ketine
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关于此项目
经验公式（希尔记法）:
C6H8N2
化学文摘社编号:
分子量:
108.14
FEMA Number:
3272
Council of Europe no.:
2210
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
14.020
EC Number:
204-618-3
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
107052
Organoleptic:
cocoa; nutty; woody; earthy
Grade:
FG, Fragrance grade, Halal, Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines
Food allergen:
no known allergens
SMILES string
Cc1cnc(C)cn1
InChI
1S/C6H8N2/c1-5-3-8-6(2)4-7-5/h3-4H,1-2H3
InChI key
LCZUOKDVTBMCMX-UHFFFAOYSA-N
biological source
synthetic
grade
FG, Fragrance grade, Halal, Kosher
agency
follows IFRA guidelines
reg. compliance
EU Regulation 1223/2009, EU Regulation 1334/2008 & 178/2002
assay
≥98%
bp
155 °C (lit.)
density
0.99 g/mL at 25 °C (lit.)
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
fragrance allergen
no known allergens
organoleptic
cocoa; nutty; woody; earthy
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General description
2,5-二甲基吡嗪是一种吡嗪类化合物，主要在烹煮或烘烤过程中，由于糖类和蛋白质之间的美拉德反应，在熟米或烘烤花生等食品中形成。
Application
- 通过重建代谢途径和增强辅因子再生，工程化大肠杆菌由L-苏氨酸高产合成2,5-二甲基吡嗪。：研究详细介绍了*大肠杆菌*的基因工程，可提高由L-苏氨酸生成2,5-二甲基吡嗪的效率。通过重建代谢途径和改善辅因子再生，研究人员实现了更高的产量，这是该化合物工业生物生产的重大进展（Liu et al., 2024）。
- 从纳豆发酵大豆中分离的芽孢杆菌菌株生物合成吡嗪的研究。：研究探讨了从纳豆中分离的*芽孢杆菌*菌株对2,5-二甲基吡嗪等吡嗪类化合物的天然生物合成。这些发现有助于了解风味化合物的微生物生产及其在食品生物技术中的潜在应用（Klosowski et al., 2021）。
Other Notes
残留物 2,6-二甲基吡嗪
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
147.2 °F - closed cup
flash_point_c
64 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Flavor components of roasted peanuts. Some low molecular weight pyrazines and pyrrole.
Mason ME, et al.
Journal of Agricultural and Food Chemistry, 14(5), 454-460 (1966)
K Yamada et al.
Biological & pharmaceutical bulletin, 17(5), 730-731 (1994-05-01)
The effects of 2,5-dimethylpyrazine (DMP) on plasma testosterone and levels of polyamines and acid phosphatase in the prostate of rat were studied. A high dose of DMP administered once daily for two weeks to juvenile male rats significantly decreased plasma
Min Hee Park et al.
Journal of food science, 76(6), C808-C816 (2011-06-01)
Perilla seeds have more than 60% of α-linolenic acid, one of omega-3 essential fatty acids. Headspace volatiles and physicochemical properties including color, fluorescence intensity, and the oxidation products in perilla oil (PO) from perilla seeds roasted at different conditions were
Identification of chemicals emitted by calling males of the Sapote fruit fly, Anastrepha serpentina.
David C Robacker et al.
Journal of chemical ecology, 35(5), 601-609 (2009-05-12)
Emissions from sexually active Anastrepha serpentina males were collected by solid-phase microextraction. Calling behavior of wild-type males showed no clear peak during the day, except that it was evident less frequently immediately after daybreak and just before dark. Calling by
W Ma et al.
Biology of reproduction, 59(6), 1317-1320 (1998-11-26)
Mature female mice, grouped in the absence of a male stimulus, exhibit a suppressed estrous cycle (the so-called Lee-Boot effect). We have designed a series of experiments to elucidate the involvement of the adrenal gland in this phenomenon. Our initial
实验方案
Separation of various pyrazines and sulfur compounds including carbon disulfide and dimethyl disulfide.
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