A76001
(±)-3-氨基-1,2-丙二醇
97%
别名:
(±)-3-氨基-1,2-羟丙烷, 1-氨基甘油, 2,3-二羟丙烷-1-胺, 3-氨基-2-羟丙醇
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关于此项目
线性分子式:
NH2CH2CH(OH)CH2OH
化学文摘社编号:
分子量:
91.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-475-8
Beilstein/REAXYS Number:
1719121
MDL number:
产品名称
(±)-3-氨基-1,2-丙二醇, 97%
InChI
1S/C3H9NO2/c4-1-3(6)2-5/h3,5-6H,1-2,4H2
InChI key
KQIGMPWTAHJUMN-UHFFFAOYSA-N
SMILES string
NCC(O)CO
assay
97%
form
liquid
refractive index
n20/D 1.492 (lit.)
bp
264-265 °C/739 mmHg (lit.)
density
1.175 g/mL at 25 °C (lit.)
Quality Level
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Application
(±)-3-氨基-1,2-丙二醇是被用作合成用于RNA干扰（RNAi）治疗的脂质样递送分子（类脂质）的一种反应物。它还用于合成生物活性模板以制备阳离子α-螺旋多肽和各种阳离子聚合物用于基因递送。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.
Anderson DG, et al.
Angewandte Chemie (International Edition in English), 115(27), 3261-3266 (2003)
Reactive and bioactive cationic ?-helical polypeptide template for nonviral gene delivery.
Gabrielson NP, et al.
Angewandte Chemie (International Edition in English), 51(5), 1143-1147 (2012)
J W Morzycki et al.
Acta poloniae pharmaceutica, 58(4), 249-256 (2001-11-06)
Three new derivatives of 3-amino-1,2-propanediol have been synthesized. Full assignments of signals in their 1H- and 13C-NMR spectra are given. The influence of these compounds on the cardiovascular system in the anaesthetized rat was examined. In contrast to CGP 12177
B W Day et al.
Chemical research in toxicology, 4(3), 359-363 (1991-05-01)
Human hemoglobin was alkylated with (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) and then treated with aqueous (+/-)-3-amino-1,2-propanediol to convert alkylated carboxyl side chains to N-(2,3-dihydroxypropyl) amides. Tryptic peptides produced from the modified protein were subjected to affinity chromatography on phenylboronic
Takaya Koseki et al.
Chemical senses, 29(8), 703-711 (2004-10-07)
Glycerol, a linear triol, is a sweet tastant for mammals but it has not previously been recognized to stimulate the sense of taste in insects. Here we show by electrophysiological experimentation that it effectively stimulates the labellar sugar receptor cell
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