A76001
(±)-3-氨基-1,2-丙二醇
97%
别名:
(±)-3-氨基-1,2-羟丙烷, 1-氨基甘油, 2,3-二羟丙烷-1-胺, 3-氨基-2-羟丙醇
质量水平
方案
97%
表单
liquid
折射率
n20/D 1.492 (lit.)
沸点
264-265 °C/739 mmHg (lit.)
密度
1.175 g/mL at 25 °C (lit.)
SMILES字符串
NCC(O)CO
InChI
1S/C3H9NO2/c4-1-3(6)2-5/h3,5-6H,1-2,4H2
InChI key
KQIGMPWTAHJUMN-UHFFFAOYSA-N
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应用
(±)-3-氨基-1,2-丙二醇是被用作合成用于RNA干扰（RNAi）治疗的脂质样递送分子（类脂质）的一种反应物。它还用于合成生物活性模板以制备阳离子α-螺旋多肽和各种阳离子聚合物用于基因递送。
警示用语：
Danger
危险声明
危险分类
Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 2
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.
Anderson DG, et al.
Angewandte Chemie (International Edition in English), 115(27), 3261-3266 (2003)
J W Morzycki et al.
Acta poloniae pharmaceutica, 58(4), 249-256 (2001-11-06)
Three new derivatives of 3-amino-1,2-propanediol have been synthesized. Full assignments of signals in their 1H- and 13C-NMR spectra are given. The influence of these compounds on the cardiovascular system in the anaesthetized rat was examined. In contrast to CGP 12177
B W Day et al.
Chemical research in toxicology, 4(3), 359-363 (1991-05-01)
Human hemoglobin was alkylated with (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) and then treated with aqueous (+/-)-3-amino-1,2-propanediol to convert alkylated carboxyl side chains to N-(2,3-dihydroxypropyl) amides. Tryptic peptides produced from the modified protein were subjected to affinity chromatography on phenylboronic
R Dijkman et al.
Biochimica et biophysica acta, 1043(1), 67-74 (1990-03-12)
This paper describes the synthesis of a number of phosphatidylcholines and phosphatidylglycols, in which one fatty acyl ester group is replaced by an acylamino function. The phospholipids, both of the alpha- and beta-type, are prepared in racemic and enantiomeric pure
Takaya Koseki et al.
Chemical senses, 29(8), 703-711 (2004-10-07)
Glycerol, a linear triol, is a sweet tastant for mammals but it has not previously been recognized to stimulate the sense of taste in insects. Here we show by electrophysiological experimentation that it effectively stimulates the labellar sugar receptor cell
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