O9808
2-羟吲哚
97%
别名:
2-吲哚酮, 羟吲哚
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关于此项目
经验公式（希尔记法）:
C8H7NO
化学文摘社编号:
分子量:
133.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-429-5
Beilstein/REAXYS Number:
114692
MDL number:
Assay:
97%
Form:
crystals
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Tao Zhang et al.
Chemical communications (Cambridge, England), 49(16), 1636-1638 (2013-01-24)
An enantioselective direct α-alkylation of 2-oxindoles with Michler's hydrol via an S(N)1-type pathway in the non-covalent activation mode using the bis-cinchona alkaloid and Brønsted acid as a co-catalyst was developed and good to high yields and enantioselectivities were obtained.
R Carpenedo et al.
Journal of neurochemistry, 70(5), 1998-2003 (1998-05-08)
Rats treated with oxindole (10-100 mg/kg i.p.), a putative tryptophan metabolite, showed decreased spontaneous locomotor activity, loss of the righting reflex, hypotension, and reversible coma. Brain oxindole levels were 0.05 +/- 0.01 nmol/g in controls and increased to 8.1 +/-
Oxindole in pathogenesis of hepatic encephalopathy.
F Moroni et al.
Lancet (London, England), 351(9119), 1861-1861 (1998-07-04)
P B Bergqvist et al.
Pharmacology & toxicology, 85(3), 138-143 (1999-10-16)
It has previously been shown that the neurodepressant L-tryptophan metabolite oxindole is increased in the blood and brain of rats with fulminant hepatic failure and in the blood of cirrhotic patients affected by chronic hepatic encephalopathy. In the present investigation
Zhigang Yang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 16(22), 6632-6637 (2010-04-22)
A highly enantioselective alpha-amination of 3-substituted oxindoles with azodicarboxylates catalyzed by a chiral Sc(OTf)(3)/N,N'-dioxide complex (Tf: triflate) has been developed and affords the corresponding 3-amino-2-oxindole derivatives in high yields (up to 98%) with excellent enantioselectivities (up to 99% ee). The
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