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线性分子式:
CH3(CH2)3B(OH)2
化学文摘社编号:
分子量:
101.94
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
EC Number:
224-607-7
Beilstein/REAXYS Number:
1733489
MDL number:
InChI key
QPKFVRWIISEVCW-UHFFFAOYSA-N
InChI
1S/C4H11BO2/c1-2-3-4-5(6)7/h6-7H,2-4H2,1H3
SMILES string
CCCCB(O)O
grade
derivatization grade (GC derivatization)
assay
≥96.0% (T)
quality
LiChropur™
reaction suitability
reagent type: derivatization reagent
reaction type: Alkylations
technique(s)
gas chromatography (GC): suitable
Quality Level
mp
90-92 °C
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相关类别
Application
- Developing a reference measurement procedure for free glycerol in human serum by two-step gas chromatography-isotope dilution mass spectrometry.: This research employs butylboronic acid in a reference measurement procedure to quantify free glycerol in human serum. The method is significant for clinical diagnostics, providing accurate and reliable measurements for metabolic studies (Chen et al., 2015).
Other Notes
气相色谱的衍生化试剂
Reagent for butylboronate.
Suitable for the derivatization of proximal difunctional compounds (a- and β-hydroxyacids; Ο-phenolic acids; enolizable a-oxo acids; 1,2- and 1,3-diols; enolizable 1,2- and 1,3-ketols; β- and γ-hydroxyamines).
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A. Darbre et al.
Handbook of Derivatives for Chromatography (1970)
D.R. Knapp
Handbook of Analytical Derivatization Reactions (1979)
L D Sutton et al.
Biochemical and biophysical research communications, 134(1), 386-392 (1986-01-14)
The cholesterol esterase and lipoprotein lipase catalyzed hydrolyses of the water-soluble substrate p-nitrophenyl butyrate are competitively inhibited by butaneboronic acid and phenylboronic acid. Phenyl-n-butylborinic acid has been synthesized and characterized as an ultrapotent transition state analog inhibitor: Ki = 2.9
Alicja J Copik et al.
Inorganic chemistry, 44(5), 1160-1162 (2005-03-01)
Metalloproteases utilize their active site divalent metal ions to generate a nucleophilic water/hydroxide. For methionine aminopeptidases (MetAPs), the exact location of this nucleophile, as well as of the substrate, with respect to the active site metal ion is unknown. In
L C Taylor et al.
Rapid communications in mass spectrometry : RCM, 8(3), 265-273 (1994-03-01)
Liquid chromatography (LC) combined with atmospheric pressure chemical ionization mass spectrometry was used to identify phase I and II metabolites of the drug BW 1370U87 in dog and human urine. Additional analysis of individual high-performance liquid chromatograph fractions collected from
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