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Merck
CN

19667

丁基硼酸

derivatization grade (GC derivatization), LiChropur, ≥96.0% (T)

别名:

1-丁烷硼酸

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关于此项目

线性分子式:
CH3(CH2)3B(OH)2
化学文摘社编号:
分子量:
101.94
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
EC Number:
224-607-7
Beilstein/REAXYS Number:
1733489
MDL number:
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InChI key

QPKFVRWIISEVCW-UHFFFAOYSA-N

InChI

1S/C4H11BO2/c1-2-3-4-5(6)7/h6-7H,2-4H2,1H3

SMILES string

CCCCB(O)O

grade

derivatization grade (GC derivatization)

assay

≥96.0% (T)

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Alkylations

technique(s)

gas chromatography (GC): suitable

Quality Level

mp

90-92 °C

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相关类别

Application


  • Developing a reference measurement procedure for free glycerol in human serum by two-step gas chromatography-isotope dilution mass spectrometry.: This research employs butylboronic acid in a reference measurement procedure to quantify free glycerol in human serum. The method is significant for clinical diagnostics, providing accurate and reliable measurements for metabolic studies (Chen et al., 2015).

Other Notes

气相色谱的衍生化试剂
Reagent for butylboronate.
Suitable for the derivatization of proximal difunctional compounds (a- and β-hydroxyacids; Ο-phenolic acids; enolizable a-oxo acids; 1,2- and 1,3-diols; enolizable 1,2- and 1,3-ketols; β- and γ-hydroxyamines).

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A. Darbre et al.
Handbook of Derivatives for Chromatography (1970)
D.R. Knapp
Handbook of Analytical Derivatization Reactions (1979)
L D Sutton et al.
Biochemical and biophysical research communications, 134(1), 386-392 (1986-01-14)
The cholesterol esterase and lipoprotein lipase catalyzed hydrolyses of the water-soluble substrate p-nitrophenyl butyrate are competitively inhibited by butaneboronic acid and phenylboronic acid. Phenyl-n-butylborinic acid has been synthesized and characterized as an ultrapotent transition state analog inhibitor: Ki = 2.9
Alicja J Copik et al.
Inorganic chemistry, 44(5), 1160-1162 (2005-03-01)
Metalloproteases utilize their active site divalent metal ions to generate a nucleophilic water/hydroxide. For methionine aminopeptidases (MetAPs), the exact location of this nucleophile, as well as of the substrate, with respect to the active site metal ion is unknown. In
L C Taylor et al.
Rapid communications in mass spectrometry : RCM, 8(3), 265-273 (1994-03-01)
Liquid chromatography (LC) combined with atmospheric pressure chemical ionization mass spectrometry was used to identify phase I and II metabolites of the drug BW 1370U87 in dog and human urine. Additional analysis of individual high-performance liquid chromatograph fractions collected from

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