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经验公式(希尔记法):
C20H24ClNO · HCl
化学文摘社编号:
分子量:
366.32
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
239-067-8
MDL number:
InChI key
UNPLRYRWJLTVAE-UHFFFAOYSA-N
InChI
1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H
SMILES string
Cl.Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Application
Cloperastine hydrochloride may be used as an analytical standard for the quantification of cloperastine in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
[Effect of cloperastine on muco-ciliary clearance].
D Olivieri et al.
Archivio Monaldi per la tisiologia e le malattie dell'apparato respiratorio, 38(5-6), 219-223 (1983-09-01)
Yukoh Sakata et al.
International journal of pharmaceutics, 335(1-2), 12-19 (2006-11-23)
Tablets containing both paracetamol (PM) and cloperastine hydrochloride (CLH) in a combination formulation prepared by standard vertical granulation technology were found to have altered pharmaceutical properties. The hardness and disintegration time of tablets containing both PM and CLH gradually increased
Nobuki Matsumoto et al.
Scientific reports, 11(1), 1492-1492 (2021-01-17)
Cancer therapy is often hampered by the disease's development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is responsible for
Cloperastine-based cough syrup and acute dystonic reactions.
Mercedes Serrano et al.
Developmental medicine and child neurology, 54(3), 287-287 (2012-02-14)
Gen Yamamoto et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(4), 523-532 (2011-04-07)
Clinically, both overactive bladder (OAB) and dysuria are known to occur in patients with cerebral infarction (CI). A few anticholinergic drugs are used to treat OAB in such patients, although the effect is not satisfactory. On the other hand, little
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