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E7879

β-雌二醇 17-醋酸酯

Name: β-雌二醇 17-醋酸酯
Brand: SIGMA

≥99%

别名:

1,3,5(10)-雌三烯-3,17β-二醇 17-醋酸酯, 3,17β-二羟基-1,3,5(10)-雌三烯 17-醋酸酯

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关于此项目

经验公式（希尔记法）:

C₂₀H₂₆O₃

化学文摘社编号:

1743-60-8

分子量:

314.42

UNSPSC Code:

12352200

NACRES:

NA.77

PubChem Substance ID:

24894658

MDL number:

MFCD00056537

Beilstein/REAXYS Number:

2625732

Assay:

≥99%

Form:

powder

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属性

sterility

non-sterile

Quality Segment

200

assay

≥99%

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow

shipped in

ambient

storage temp.

room temp

SMILES string

CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C

InChI

1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key

QAHOQNJVHDHYRN-SLHNCBLASA-N

说明

Application

β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.

Biochem/physiol Actions

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.