E7879
β-雌二醇 17-醋酸酯
≥99%
别名:
1,3,5(10)-雌三烯-3,17β-二醇 17-醋酸酯, 3,17β-二羟基-1,3,5(10)-雌三烯 17-醋酸酯
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C20H26O3
化学文摘社编号:
分子量:
314.42
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2625732
InChI
1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1
SMILES string
CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C
InChI key
QAHOQNJVHDHYRN-SLHNCBLASA-N
sterility
non-sterile
assay
≥99%
form
powder
solubility
chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow
shipped in
ambient
storage temp.
room temp
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.
Biochem/physiol Actions
β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.
Features and Benefits
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 1 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Estrogen and the Vessel Wall, 38-38 (2003)
Layer-by-Layer Films for Biomedical Applications, 517-517 (2014)
Bioactive Natural Products: Chemistry and Biology, 375-375 (2015)
Accumulation of triclosan from diet and its neuroendocrine effects in Atlantic croaker (Micropogonias undulatus) under two temperature Regimes
Hedrick-Hopper TL, et al.
Marine Environmental Research, 112(51), 52-60 (2015)
Anna Höckerstedt et al.
Journal of lipid research, 43(3), 392-397 (2002-03-15)
It has been shown that estrogens need to be metabolized to their hydrophobic estrogen ester derivatives to act as antioxidants in lipoproteins. Data suggest that 17beta-estradiol (E(2)) becomes esterified in LCAT-induced reactions and the esters are transported from HDL particles
商品
Discover Bioactive Small Molecules for ADME/Tox
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持