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Merck
CN

E7879

Sigma-Aldrich

β-雌二醇 17-醋酸酯

≥99%

别名:

1,3,5(10)-雌三烯-3,17β-二醇 17-醋酸酯, 3,17β-二羟基-1,3,5(10)-雌三烯 17-醋酸酯

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关于此项目

经验公式(希尔记法):
C20H26O3
化学文摘社编号:
分子量:
314.42
Beilstein:
2625732
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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无菌性

non-sterile

方案

≥99%

表单

powder

溶解性

chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow

运输

ambient

储存温度

room temp

SMILES字符串

CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C

InChI

1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key

QAHOQNJVHDHYRN-SLHNCBLASA-N

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应用

β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.

生化/生理作用

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

特点和优势

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

象形图

Health hazardEnvironment

警示用语:

Danger

危险声明

危险分类

Aquatic Chronic 1 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Layer-by-Layer Films for Biomedical Applications, 517-517 (2014)
Bioactive Natural Products: Chemistry and Biology, 375-375 (2015)
Accumulation of triclosan from diet and its neuroendocrine effects in Atlantic croaker (Micropogonias undulatus) under two temperature Regimes
Hedrick-Hopper TL, et al.
Marine Environmental Research, 112(51), 52-60 (2015)
Estrogen and the Vessel Wall, 38-38 (2003)
17-beta-estradiol increases neuronal excitability through MAP kinase-induced calpain activation
Zadran S, et al.
Proceedings of the National Academy of Sciences of the USA, 106(51), 21936-21941 (2009)

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