L9776
亮氨酸氨基肽酶，微粒体 来源于猪肾脏
suitable for protein sequencing, BioReagent, lyophilized powder
别名:
亮氨肽酶, 亮酰胺氨肽酶, 氨基肽酶 M, 氨肽酶M, 氨肽酶N, 组织蛋白酶 III
product line
BioReagent
form
lyophilized powder
packaging
vial of 50 μg
suitability
suitable for protein sequencing
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
正在寻找类似产品? 访问 产品对比指南
General description
亮氨酸氨肽酶 (LAP) 是一种蛋白水解酶。它是一种氨基酸水解酶，催化蛋白质或肽氨基末端亮氨酸残基的水解。LAP 在肝脏、肾脏、肺和血清中天然存在。
Application
亮氨酸氨基肽酶可用于：
- 蛋白质组学分析
- 用作蛋白质解聚反应的预处理剂
- 测试其对人重组IL-8降解的影响
Biochem/physiol Actions
在肝损伤、肝硬化、肝炎和其他疾病状态下下，血清亮氨酸氨基肽酶(LAP )活性会增加，因此 LAP 可用作药物引起的肝损伤生物标志物。LAP表达异常会导致肿瘤细胞增殖、血管生成和侵袭，因此也可用作癌症相关的生物标志物。
Other Notes
一个单位在37°C 下 pH 7.2 时每分钟将水解 1.0μ摩尔 L-亮氨酸-对硝基苯胺为 L -亮氨酸和对硝基苯胺（25°C 下可获得活性约为37°C 下的 40%）。以 L-亮氨酸对硝基苯胺为底物得到的活性是以 L-亮氨酸酰胺为底物得到的活性的 2-5 倍。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Simone Giaveri et al.
Advanced materials (Deerfield Beach, Fla.), 33(44), e2104581-e2104581 (2021-09-24)
The billion tons of synthetic-polymer-based materials (i.e. plastics) produced yearly are a great challenge for humanity. Nature produces even more natural polymers, yet they are sustainable. Proteins are sequence-defined natural polymers that are constantly recycled when living systems feed. Digestion
A Kehlen et al.
European cytokine network, 12(2), 316-324 (2001-06-12)
In rheumatic joints, high concentrations of interleukin-8 (IL-8) have been measured in synovial fluid and in pannus tissue. In both locations aminopeptidase N (APN)/CD13, an exopeptidase with reported activity towards IL-8 is also present. The surprising stability of IL-8 in
Fluorescent probes for detection and bioimaging of leucine aminopeptidase
Y Chen
Materials today chemistry, 15, 100216-100216 (2020)
Yong Huang et al.
Analytical chemistry, 91(13), 8085-8092 (2019-05-31)
Drug-induced liver injury (DILI) is a frequent cause of hepatic dysfunction as well as the single most frequent reason for removing approved medications from the market, and multispectral optoacoustic tomography (MSOT) is an emerging and noninvasive imaging modality for diagnosing
Sudha Warrier et al.
Cell biology international, 36(12), 1137-1143 (2012-07-10)
Glioblastoma is one of the most common malignant tumours in adults, with an average life expectancy of less than 1 year. The high mortality of glioblastomas is attributed to its resistance to conventional chemotherapeutic agents. Numerous studies have established the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持