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经验公式(希尔记法):
C15H10N2O6
化学文摘社编号:
分子量:
314.25
UNSPSC Code:
12352108
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1505254
Form:
crystalline
产品名称
3-马来酰亚胺基苯甲酸 N -羟基琥珀酰亚胺酯, crystalline
InChI key
LLXVXPPXELIDGQ-UHFFFAOYSA-N
SMILES string
O=C1CCC(N1OC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O)=O
InChI
1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
form
crystalline
reaction suitability
reagent type: cross-linking reagent
mp
175-177 °C (lit.)
solubility
DMSO: ≤20 mg/mL
functional group
NHS ester
maleimide
storage temp.
−20°C
Quality Level
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Application
3-马来酰亚胺基苯甲酸 N-琥珀酰亚胺酯已被用于:
- 拟南芥中花粉的固定
- 作为MS培养基的成分使桉树根毛中的纤维状肌动蛋白保持稳定
- 兰州百合纤维状肌动蛋白标记的花粉管的固定
3-马来酰亚胺基苯甲酸 N-羟基琥珀酰亚胺酯(MBS)已用作蛋白质交联剂。它已被用于稳定植物组织样品中的肌动蛋白丝。
对伯胺和巯基具有反应性的双异官能化交联剂。通常,初始反应在 pH 为 7.0 时,通过酰胺键偶联至含伯胺的分子,然后在相同 pH 通过硫醚偶联至含巯基的化合物。用于制备酶免疫交联剂和半抗原载体分子偶联物。
Biochem/physiol Actions
3-马来酰亚胺基苯甲酸N-琥珀酰亚胺可用作固定剂,用于保持花粉管纤维状肌动蛋白的分布。它用于花粉管时产生的损伤较少。
General description
可能需要在偶联缓冲液中加入溶剂(至少5%)以维持溶解度
Other Notes
芳基马来酰亚胺比烷基马来酰亚胺连接基更不稳定。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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