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Merck
CN

M6045

2-甲基-4-异噻唑啉-3-酮 盐酸盐

≥99%

别名:

MIT, 甲基异噻唑啉酮 盐酸盐

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关于此项目

经验公式（希尔记法）:
C4H5NOS · HCl
化学文摘社编号:
26172-54-3
分子量:
151.61
UNSPSC Code:
51102829
NACRES:
NA.76
PubChem Substance ID:
24897073
EC Number:
247-499-3
Beilstein/REAXYS Number:
3993054
MDL number:
MFCD06804636

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产品名称

2-甲基-4-异噻唑啉-3-酮 盐酸盐, ≥99%

InChI key

SJXPQSRCFCPWQQ-UHFFFAOYSA-N

InChI

1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H

SMILES string

Cl[H].CN1SC=CC1=O

Quality Level

200

biological source

synthetic

assay

≥99%

form

powder

concentration

≤ 100%

technique(s)

cell culture | mammalian: suitable

color

white to beige

mp

165—170 °C ((329 - 338 °F) at ca.990.4 hPa)

solubility

water: soluble 10.0 — 10.4 mg/mL, clear, colorless to faint yellow or tan

suitability

suitable for component for culture media

application(s)

microbiology

mode of action

protein synthesis | interferes

storage temp.

2-8°C

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相关类别

Application

盐酸甲基异噻唑啉酮(MIT HCl)已用于：


  • 研究MIT作为细胞毒性物质，对支气管上皮细胞(BEAS-2B)的影响，及在凋亡性细胞死亡中的作用
  • 研究酪氨酸磷酸化对神经轴突和树突发育过程中粘着斑激酶(FAK)活性的影响

Biochem/physiol Actions

2-甲基-4-异噻唑啉-3-酮盐酸盐(MIT HCl)是皮肤致敏物，会引起接触性皮炎和过敏。它在化妆品行业中广泛用作防腐剂。盐酸甲基异噻唑啉酮是一种神经毒素，过久暴露可能会引起神经元细胞死亡和神经突生长抑制。

General description

2-甲基-4-异噻唑啉-3-酮盐酸盐（MIT HCl，盐酸甲基异噻唑啉酮）是合成异噻唑啉酮的衍生物。

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1

supp_hazards

EUH071

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000504428
0000504427
0000504427
0000504428
0000502096

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