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经验公式(希尔记法):
C15H12O8
化学文摘社编号:
分子量:
320.25
UNSPSC Code:
41116107
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O1[C@@H]([C@H](C(=O)c3c1cc(cc3O)O)O)c2cc(c(c(c2)O)O)O
InChI key
KJXSIXMJHKAJOD-LSDHHAIUSA-N
Biochem/physiol Actions
Antioxidant, anti-cancer flavanonol with anti-alcohol intoxication effects, significantly impacts metabolic regulation and cancer chemoprevention through pathways like AMPK and SPHK1/mTOR.Dihydromyricetin (DHM) is a potent flavonoid known for its antioxidative, anti-inflammatory, anticancer, and antimicrobial properties, and plays a key role in modulating metabolism with minimal side effects. It operates by either scavenging or generating reactive oxygen species (ROS) to selectively target cancer cells, while sparing normal cells. DHM acts through multiple pathways including AMPK, affecting autophagy and glucose transport. Additionally, Dihydromyricetin inhibits ferroptosis via the SPHK1/mTOR pathway, modulates the Prx2 cascade through Nrf2, and contributes to cancer prevention and diabetes treatment by altering redox balance, gene expression, and improving metabolism, also involving AMPK, PI3K/Akt, PPAR pathways, and microRNAs.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable