30 min., 135 °C at ≤ 300 mbar (5
psi) or, 22 forward cycles, 30 min., 135 °C at ≤ 300 mbar (5 psi) and
3 reverse cycles, 30 min., 135 °C at 135 °C at ≤
defined in 21 CFR 210.3 (b) (6).
Typical air pressure drop for Optiseal® cartridges
with 0.2 μm Aervent® membrane.
Particle shedding in air after SIP, 30 minutes at 135 ºC
for Optiseal® cartridges
liter water flush per 10-inch
(25.4 cm) cartridge.
USP 88> Safety Autoclaved (126 °C, 60 minutes) cartridges are non-toxic per USP 88> Safety Test.
Non-Fiber Releasing Charged Durapore® CCGL and
-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Component Material Toxicity Component materials meet the criteria of the USP 88> Reactivity Test for Class VI Plastics. This product
is
Neuraminidase
The enzyme is supplied in 20 mM Trizma-HCl, pH 7.5.
Specific activity: 135 units/mg protein
Unit Definition: One unit will hydrolyze 1 mole of
4-methylumbelliferyl
releasing” filter as defined in 21 CFR 210.3 (b) (6).
Component Material Toxicity Component materials were tested and meet the criteria of the USP 88> Reactivity Test for Class VI plastics.
Indirect
Immunol., 158, 3408-
3416 (1997).
6. Waibler, Z., et al., J. Cell Sci., 114,
3873-3884 (2001).
7. Herrenknecht, K., et al., Proc. Natl. Acad. Sci.
USA, 88, 9156-9160 (1991).
8. Yan
for 30 cycles of 30 minutes at 135 °C.
Non-Fiber Releasing Aervent® membrane meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3
(b) (6).
Component Material Toxicity
Matunis, M.J., et al., J. Cell Biol., 135, 1457-1470
(1996).
2. Kamitani, T., et al., J. Biol. Chem., 272, 14001-
14004 (1997).
3. Mahajan, R., et al., Cell, 88, 97-107 (1997).
4. Bayer, P., et
Matunis, M.J., et al., J. Cell Biol., 135, 1457-1470
(1996).
2. Kim, K.I., et al., J. Cell. Physiol., 191, 257-268
(2002).
3. Mahajan, R., et al., Cell, 88, 97-107 (1997).
4. Bayer, P., et al.
KOREA Millipore Korea Co. Ltd./Suite 711, Korea City Air Terminal Building/159-6, Samsung-Dong, Kangnam-Ku/Seoul 135-728/Tel. (822) 551-0230/
Fax (822) 551-0288
MALAYSIA Millipore Asia Ltd./Suite