搜索范围
184861
应用筛选条件
关键词:'184861'
显示 1-30 #N/A 374 条结果 关于 "184861" 范围 论文
N A Wilson et al.
Prostaglandins, leukotrienes, and essential fatty acids, 152, 102037-102037 (2019-12-08)
Omega-3 DHA is important for the prevention of preterm birth, however there is limited knowledge of the determinants of omega-3 status during pregnancy. The primary objective of this systematic review was to synthesise data from existing studies assessing relationships between
Chukwudi O Onwosi et al.
Environmental technology, 41(24), 3178-3190 (2019-04-16)
We investigated a number of microbiological activities in the soil to serve as biomonitoring tools in assessing the ecotoxicity of diesel-contaminated soil samples during the different periods of bioremediation. Sawdust was used as the biostimulant for the biodegradation of artificial
Wen-Ting Hsiao et al.
Nutrition research and practice, 13(4), 286-294 (2019-08-08)
Docosahexaenoic acid (DHA), an n-3 long chain polyunsaturated fatty acid (LCPUFA), is acquired by dietary intake or the in vivo conversion of α-linolenic acid. Many enzymes participating in LCPUFA synthesis are regulated by peroxisome proliferator-activated receptor alpha (PPARα). Therefore, it
Cynthia Aslan et al.
Life sciences, 258, 118094-118094 (2020-07-17)
Docosahexaenoic acid (DHA) as an omega 3 free fatty acid has been reported to exert anti-angiogenesis effects. However, our current understanding regarding the precise mechanisms of such effects is still limited. Exosomes secreted by cancer cells may act as angiogenesis
Yan Luo et al.
Toxicology and applied pharmacology, 403, 115159-115159 (2020-07-30)
Dihydroartemisinin (DHA) is an artemisinin derivative commonly used in malaria therapy, and a growing number of studies have focused on the potent anticancer activity of DHA. However, the reproductive toxicity of anticancer drugs is a major concern for young female
Thomas R Lane et al.
Antiviral research, 182, 104908-104908 (2020-08-18)
We have recently identified three molecules (tilorone, quinacrine and pyronaridine tetraphosphate) which all demonstrated efficacy in the mouse model of infection with mouse-adapted Ebola virus (EBOV) model of disease and had similar in vitro inhibition of an Ebola pseudovirus (VSV-EBOV-GP)
Daniel González-Hedström et al.
Nutrients, 13(1) (2020-12-31)
Aging is associated with a progressive decline in skeletal muscle mass, strength and function (sarcopenia). We have investigated whether a mixture of algae oil (25%) and extra virgin olive oil (75%) could exert beneficial effects on sarcopenia. Young (3 months)
Heitor O Santos et al.
Nutrients, 12(10) (2020-10-22)
Cardiovascular diseases remain a global challenge, and lipid-associated biomarkers can predict cardiovascular events. Extensive research on cardiovascular benefits of omega-3 polyunsaturated fatty acids (n3-PUFAs) is geared towards fish oil supplementation and fish-rich diets. Nevertheless, vegetarianism and veganism are becoming more
Bo Yang et al.
Psychotherapy and psychosomatics, 88(4), 215-224 (2019-07-04)
Endocannabinoids (ECs) are one type of bioactive endogenous neuroinflammatory mediator derived from polyunsaturated fatty acids (PUFAs), which may regulate the emotional processes. Here, we assessed the effect of ω-3 PUFAs on EC levels, which may be the novel targets for
Minal Jaggar et al.
Frontiers in neuroendocrinology, 56, 100815-100815 (2019-12-06)
Sex is a critical factor in the diagnosis and development of a number of mental health disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease, multiple sclerosis, anorexia nervosa and others; likely due to differences in sex steroid hormones and genetics.
DHA Attenuates Hypoxia/Reoxygenation Injury by Activating SSeCKS in Human Cerebrovascular Pericytes.
Yanli Yu et al.
Neurochemical research, 45(2), 310-321 (2019-11-30)
Docosahexaenoic acid (DHA) can alleviate cerebral ischemia/reperfusion injury by reducing blood-brain barrier permeability and maintaining its integrity, accompanied by an increased Ang-1/Ang-2 ratio; however, the underlying mechanisms of these effects remain unclear. Src-suppressed C kinase substrates (SSeCKS), a substrate of
Yunzhi Liu et al.
Oxidative medicine and cellular longevity, 2020, 8096847-8096847 (2020-09-11)
Acetaminophen (APAP) toxicity is the leading cause of drug-induced liver failure, which is closely related to mitochondrial dysfunction and oxidative damage. Studies in clinical trials and in animal models have shown that omega-3 polyunsaturated fatty acids (n-3 PUFAs) affect the
Einar Vargas-Bello-Pérez et al.
Veterinary sciences, 6(2) (2019-06-20)
A prior study in bovine mammary (MACT) cells indicated that long-chain fatty acids (LCFA) C16:0 and C18:0, but not unsaturated LCFA, control transcription of milk fat-related genes partly via the activation of peroxisome proliferator-activated receptor gamma (PPARγ). However, in that
Shuli Yang et al.
Journal of diabetes research, 2019, 7074042-7074042 (2020-01-21)
To investigate the effects of cod-liver oil on metabolic status and high-sensitivity C-reactive protein (hs-CRP) in patients with gestational diabetes mellitus (GDM). This study was a randomized, double-blinded, placebo-controlled trial with the allocation ratio of 1 : 1. The contents of EPA
Évelin Maria Brand et al.
PloS one, 14(10), e0222786-e0222786 (2019-10-03)
TB/HIV coinfection is a serious public health issue in Brazil, and patients with coinfection have difficulty adhering to treatments. Directly observed treatment (DOT) has been recommended by the World Health Organization, considering the vulnerability of those affected. The purpose is
Janne Bredehöft et al.
ACS chemical neuroscience, 10(10), 4394-4406 (2019-09-13)
Lipids, including omega-3 polyunsaturated fatty acids (n-3-PUFAs), modulate brain-intrinsic inflammation during systemic inflammation. The vascular organ of the lamina terminalis (OVLT) is a brain structure important for immune-to-brain communication. We, therefore, aimed to profile the distribution of several lipids (e.g.
Mutay Aslan et al.
Toxicology in vitro : an international journal published in association with BIBRA, 66, 104836-104836 (2020-03-30)
This study evaluated polyunsaturated fatty acids (PUFAs) in human kidney epithelial cells exposed to diclofenac (DCL) toxicity. Kidney cells were treated with DCL to induce cytotoxicity and thymoquinone (TQ) was administered to decrease cytotoxic effects. Levels of arachidonic acid (AA
Catherine Chunda-Liyoka et al.
BMC pregnancy and childbirth, 20(1), 93-93 (2020-02-12)
Nut butter-based Ready to Use Supplemental Foods (RUSF) are an effective way to add nutrients and calories to diets of malnourished and food insecure populations. The RUSF formulations have been further modified to add micronutrients including iron and folic acid
Walaa F Awadin et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 228, 108668-108668 (2019-11-13)
This study was performed to evaluate the effects of omega-3 supplementation on growth performance, clinical signs, post-mortem lesions, haemagglutination inhibition (HI) antibody titres, gene expression and histopathology in quails (Coturnix coturnix japonica) infected with Newcastle disease virus (NDV) and avian
Ahmed A Elmarakby et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(11), 1669-1680 (2019-07-28)
Recent studies suggest a potential role of bioactive lipids in acute kidney injury induced by lipopolysaccharide (LPS). The current study was designed to determine the profiling activities of various polyunsaturated fatty acid (PUFA) metabolizing enzymes, including lipoxygenases (LO), cyclooxygenase, and
Lili Zhu et al.
Frontiers in pharmacology, 11, 587470-587470 (2021-03-05)
Dihydroartemisinin (DHA), a sesquiterpene lactone with endoperoxide bridge, is one of the derivatives of artemisinin. In addition to having good antimalarial properties, DHA exhibits anticancer effects including against malignant solid tumors. However, the mechanism by which DHA inhibits the progression
Zhuo-Hao Liu et al.
International journal of molecular sciences, 21(19) (2020-09-30)
Spinal cord injury (SCI) is associated with disability and a drastic decrease in quality of life for affected individuals. Previous studies support the idea that docosahexaenoic acid (DHA)-based pharmacological approach is a promising therapeutic strategy for the management of acute
Lichchavi D Rajasinghe et al.
Frontiers in immunology, 11, 2179-2179 (2020-10-31)
Airway exposure of lupus-prone NZBWF1 mice to crystalline silica (cSiO2), a known trigger of human autoimmune disease, elicits sterile inflammation and alveolar macrophage death in the lung that, in turn, induces early autoimmune onset and accelerates lupus progression to fatal
Tamara Hoppenbrouwers et al.
Frontiers in immunology, 11, 748-748 (2020-05-21)
Allergy is becoming a rapidly increasing problem worldwide, and in vitro models are frequently used to study the mechanisms behind the different types of allergic response. The dendritic cell (DC)-T-cell model can be used to study sensitization. However, lipopolysaccharide (LPS)
Angela Maria Rizzo et al.
Cells, 10(1) (2021-01-21)
(1) Background: Lipid metabolism is a fundamental hallmark of all tumors, especially of breast cancer. Few studies describe the different lipid metabolisms and sensitivities to the microenvironment of breast cancer cell subtypes that influence the proliferation, aggressiveness, and success of
Shiqi Yuan et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 126, 110102-110102 (2020-03-22)
Monocytes play a crucial role in Alzheimer's disease (AD), and docosahexaenoic acid (DHA) has a neuroprotective effect for many neurodegenerative diseases. However, mechanisms that regulate monocyte and Aβ protein interaction in AD and the effects of DHA on monocytes in
Michael J Lynch et al.
Nature chemical biology, 15(10), 959-965 (2019-08-14)
The flagellar hook protein FlgE from spirochaete bacteria self-catalyzes the formation of an unusual inter-subunit lysinoalanine (Lal) crosslink that is critical for cell motility. Unlike other known examples of Lal biosynthesis, conserved cysteine and lysine residues in FlgE spontaneously react
Mónica B Betancor et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 240, 110372-110372 (2019-11-02)
Elongation of very long-chain fatty acid 4 (Elovl4) proteins are involved in the biosynthesis of very long-chain (>C24) fatty acids and in many teleost fish species they are key enzymes in the pathway for the production of docosahexaenoic acid (DHA;
María Carmen Sánchez et al.
Microorganisms, 9(2) (2021-03-07)
Microbial biofilm modeling has improved in sophistication and scope, although only a limited number of standardized protocols are available. This review presents an example of a biofilm model, along with its evolution and application in studying periodontal and peri-implant diseases.
Michael Armstrong et al.
Prostaglandins & other lipid mediators, 151, 106483-106483 (2020-10-01)
A liquid chromatography tandem mass spectrometry-based method for the quantitation of 39 lipid mediators in four sample types and in two mouse strains is described. The method builds upon existing methodologies for analysis of lipid mediators by A) utilizing a
1/13