Stephanie Gourdain et al.
Nucleosides, nucleotides & nucleic acids, 29(7), 542-546 (2010-07-01)
Previously reported syntheses of the photoaffinity label 5-azido-2'-deoxyuridine are rather inefficient and involve the tedious preparation of a 5-nitro intermediate. To overcome these inconveniences, we have developed a new approach from the commercially available 5-bromo-2'-deoxyuridine nucleoside. Our synthetic route makes