Li-Sophie Z Rathje et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1515-1520 (2014-01-30)
Oncogenes deregulate fundamental cellular functions, which can lead to development of tumors, tumor-cell invasion, and metastasis. As the mechanical properties of cells govern cell motility, we hypothesized that oncogenes promote cell invasion by inducing cytoskeletal changes that increase cellular stiffness.