modified silica tlc plates

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TLC plates, with silica gel, gypsum as binder, International Pharmacopoeia compliant, for identification of Atenolol and Chlorthalidone in tablets.

Small Molecule HPLC

Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of

TLC Plate Selection Guide

Thin layer chromatography (TLC), an analytical technique often used to separate and identify compounds present in a given mixture, can also be used to determine the purity of a particular substance within that mixture

PLC Plates for Separations from Milligrams to Grams

Our Preparative layer (PLC) plates allow separation and purification of samples varying in quantity – from milligrams to grams.

Thin-Layer Chromatography Process

What causes a dissolved mixture to separate when applied to a TLC plate? The thin-layer chromatography process relies on capillary forces. During development of the chromatogram, the mixture of substances is first transported by the mobile phase, then resides on

Tips & Tricks for Thin-Layer Chromatography

Thin Layer Chromatography Troubleshooting: This article details TLC tips and tricks that one must consider while performing different steps of the technique.

Thin Layer Chromatography Identification Test for Dextromethorphan following European Pharmacopeia Monograph on Silica Gel G 254 Plates

Silica gel G 254 plates are suitable for analysis of Dextromethorphan following the European pharmacopeia monograph.

Determination of Quinine in Tonic Water and Caffeine in Coffee and Cola Drinks Using TLC-MS

HPTLC–MS analysis of quinine in tonic water and caffeine in coffee and cola drinks. Tonic and cola drinks decarbonized through ultrasonication, and coffee extracted through PTFE filter.

Sildenafil Citrate USP Method Using HPTLC Plates for the Limit of Imidazole Test

In the present study we demonstrate compliance of silica gel 60 F254 HPTLC plates with USP requirements, and how HPTLC plates are suitable for the Sildenafil citrate-Limit of Imidazole test.

History of Thin-Layer Chromatography

Thin layer chromatography

Qualitative Thin Layer Chromatography Analysis Ginkgo

Qualitative Thin Layer Chromatography Analysis of Flavonoids and Quantification of Terpene Lactones in Ginkgo Biloba Extracts and Tablets

Detection and Determination of Caffeine, Taurine and Arginine in Shampoos by HPTLC

The modern thin-layer chromatography (TLC) offers advantages also in the field of cosmetics to quickly and simultaneously analyze samples with densitometric detection.

Determination of Caffeine in Energy Drinks with HPTLC-MS

Thin layer chromatography coupled with mass spectrometry does not require substantial sample preparation. Energy drinks can be applied without dilution directly onto the TLC plate.

Catalyst Screening followed by TLC-MS for Reaction Progress Analysis using KitAlysis™

Catalyst screening, KitAlysis™ High-Throughput Screening Kits, Thin layer chromatography (TLC), parallel analysis, parallel synthesisigh-Throughput Buchwald-Hartwig Amination Reaction Screening Kit, TLC-MS analysis

Determination of Stevioside and Rebaudioside A in Stevia leaves, beverages and food additives using HPTLC-MS

HPTLC-MS was used to analyze stevioside and rebaudioside in artificial sweeteners, stevia plants, cola and isotonic drinks with a minimum of sample preparation.

Custom HPLC Column Request

Supelco offers premium quality custom packed HPLC columns for your challenging application needs. Use this webform to order a non-stock product HPLC column from our multiple particles and chemistry options.

Synthesis of Melting Gels Using Mono-Substituted and Di-Substituted Alkoxysiloxanes

Ultra-High Performance Liquid Chromatography (UHPLC) with the Ascentis® Express Phenyl-Hexyl Column

Two Distinct Sample Prep Approaches to Overcome Matrix Effect in LC/MS of Serum or Plasma Samples

This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.

HybridSPE-Phospholipid Technology

This Sigma-Aldrich article discusses how the HybridSPE-Phospholipid Technology works and how the phospholipids are removed.

QuEChERS Sample Preparation Method

QuEChERS is a ‘Quick, Easy, Cheap, Effective, Rugged and Safe’ sample cleanup method used to prepare food and agricultural samples for pesticides analysis. QuEChERS is based on the Solid Phase Extraction (SPE) technique of sample preparation.

Silver Nanomaterials for Biological Applications

Silver nanomaterials have unique physical, chemical, and optical properties that are currently being leveraged for a wide variety of biological applications.

Inorganic Nanoparticles — Unique Properties and Novel Applications

This article highlights the rich variety of structures and properties that can be realized in materials based on inorganic nanoparticles, and points to outstanding fundamental questions raised in controlling these properties.

Barrier Formation and Permeability Assays using Millicell^® Hanging Cell Culture Inserts

How to set up barrier formation and permeability assays using cell culture inserts and TEER measurements.