Merck
CN

CACNA1D

calcium channel, voltage-dependent, L type, alpha 1D subunit

别名:
CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, SANDD
物种:
UniProtKB ID:
基因ID:
  • Human(776) Summary: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
  • Mouse(12289) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Rat(29716) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • sheep(101106371) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic cat(101088394) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Domestic Rabbit(100327259) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • chicken(395895) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Horse(100051186) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • dog(484724) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic guinea pig(100726255) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • cow(408013) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • naked mole-rat(101714832) calcium channel, voltage-dependent, L type, alpha 1D subunit

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Small Molecule - Allosteric Modulator

货号
说明
物种
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
加巴喷丁, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
尼莫地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
桂利嗪, European Pharmacopoeia (EP) Reference Standard,
物种
human
尼莫地平, United States Pharmacopeia (USP) Reference Standard,
物种
human
非洛地平, United States Pharmacopeia (USP) Reference Standard,
物种
human
非洛地平, British Pharmacopoeia (BP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-CACNA1D 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Monoclonal Anti-CACNA1D antibody produced in mouse, clone S48A-9, 1 mg/mL, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Calcium Channel Antibody, Voltage Gated α 1D, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

货号
说明
物种
Margatoxin, ,
物种
mouse, rat, human
苯磺酸氨氯地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
(±)-维拉帕米 盐酸盐, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
维拉帕米 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
苯磺酸氨氯地平, ≥98% (HPLC),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CACNA1D,
物种
human