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GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5

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Small Molecule - Agonist

Product Number
Description
Species
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Thiopental, United States Pharmacopeia (USP) Reference Standard,
Species
human
Propofol, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propofol, United States Pharmacopeia (USP) Reference Standard,
Species
human
Propofol, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Ro 15-4513, solid,
Species
rat, human
SR-95531, ≥98% (HPLC), powder,
Species
human
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GABA A Receptor-Atto 488 antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-FITC antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Horseradish Peroxidase antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-R-Phycoerythrin antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
L-655,708, ≥98% (HPLC), powder,
Species
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GABRA5,
Species
human