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GABRA6

gamma-aminobutyric acid (GABA) A receptor, alpha 6

Synonyms:
Species:
Human GABRA6 (2559), Mouse Gabra6 (14399), Rat Gabra6 (29708), dog GABRA6 (489145), domestic cat GABRA6 (101093992), cow GABRA6 (539194), sheep GABRA6 (101117503), Horse GABRA6 (100070890), naked mole-rat Gabra6 (101720123), domestic guinea pig Gabra6 (100720891)
UniProtKB ID:
Q16445, A8K096, Q4VAV2
Gene ID:
  • Human(2559) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14399) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
  • Rat(29708) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • dog(489145) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic cat(101093992) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • cow(539194) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • sheep(101117503) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • Horse(100070890) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • naked mole-rat(101720123) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic guinea pig(100720891) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • chicken(395931) gamma-aminobutyric acid (GABA) A receptor, alpha 6

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Small Molecule - Agonist

Product Number
Description
Species
T101
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
G019
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
P9159
Piperidine-4-sulfonic acid, ,
Species
human
A2129
γ-Aminobutyric acid, ≥99%,
Species
human, rat
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
D4000
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
BP1031
Propofol, British Pharmacopoeia (BP) Reference Standard,
Species
human
1572503
Propofol, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1663
Propofol, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1661002
Thiopental, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
R109
Ro 15-4513, solid,
Species
rat, human
S106
SR-95531, ≥98% (HPLC), powder,
Species
human
D4000
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
1273808
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
G7795
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
G0295
Anti-GABAA Receptor (α6 subunit), Cytosolic Loop antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
rat
Application
western blot
AB5453
Anti-GABA A Receptor α6 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunohistochemistry
western blot
G5544
Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
N142
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
V8261
(±)-Vigabatrin, ,
Species
human
D126608
2,6-Diisopropylphenol, 97%,
Species
human
T-039
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
1672206
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
EHU000761
MISSION® esiRNA, targeting human GABRA6,
Species
human