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GABRA6

gamma-aminobutyric acid (GABA) A receptor, alpha 6

Synonyms:
Species:
Human GABRA6 (2559), Mouse Gabra6 (14399), Rat Gabra6 (29708), dog GABRA6 (489145), domestic cat GABRA6 (101093992), cow GABRA6 (539194), sheep GABRA6 (101117503), Horse GABRA6 (100070890), naked mole-rat Gabra6 (101720123), domestic guinea pig Gabra6 (100720891)
UniProtKB ID:
Q16445, A8K096, Q4VAV2
Gene ID:
  • Human(2559) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14399) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
  • Rat(29708) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • dog(489145) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic cat(101093992) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • cow(539194) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • sheep(101117503) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • Horse(100070890) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • naked mole-rat(101720123) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic guinea pig(100720891) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • chicken(395931) gamma-aminobutyric acid (GABA) A receptor, alpha 6

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Small Molecule - Agonist

Product Number
Description
Species
T101
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
G019
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
P9159
Piperidine-4-sulfonic acid, ,
Species
human
A2129
γ-Aminobutyric acid, ≥99%,
Species
human, rat
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
D4000
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
BP1031
Propofol, British Pharmacopoeia (BP) Reference Standard,
Species
human
1572503
Propofol, United States Pharmacopeia (USP) Reference Standard,
Species
human
Y0000016
Propofol, European Pharmacopoeia (EP) Reference Standard,
Species
human
1661002
Thiopental, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
R109
Ro 15-4513, solid,
Species
rat, human
S106
SR-95531, ≥98% (HPLC), powder,
Species
human
D4000
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
1273808
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
G7795
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
G0295
Anti-GABAA Receptor (α6 subunit), Cytosolic Loop antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
rat
Application
western blot
AB5453
Anti-GABA A Receptor α6 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunohistochemistry
western blot
G5544
Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
N142
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
V8261
(±)-Vigabatrin, ,
Species
human
D126608
2,6-Diisopropylphenol, 97%,
Species
human
T-039
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
PHR1600
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
EHU000761
MISSION® esiRNA, targeting human GABRA6,
Species
human