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GABRB1

gamma-aminobutyric acid (GABA) A receptor, beta 1

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2560) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14400) gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
  • Rat(25450) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • Zebrafish(100331377) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • sheep(101122358) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • naked mole-rat(101717539) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic guinea pig(100719515) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic cat(101097640) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • dog(100687745) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • cow(282239) gamma-aminobutyric acid (GABA) A receptor, beta 1

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Small Molecule - Agonist

Product Number
Description
Species
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Thiopental, United States Pharmacopeia (USP) Reference Standard,
Species
human
Propofol, British Pharmacopoeia (BP) Reference Standard,
Species
human
Propofol, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
SR-95531, ≥98% (HPLC), powder,
Species
human
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse
2,6-Diisopropylphenol, 97%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABRB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-GABA-RB (pSer434) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-GABRB1 (Ab-434) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-GABA A Receptor beta 1 (GABRB1) Antibody, clone 1Q3A9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-GABA A Receptor β 1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabrb1,
Species
mouse
MISSION® esiRNA, targeting human GABRB1,
Species
human