Skip to Content
Merck
CN

GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2561) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]
  • Mouse(14401) gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
  • Rat(25451) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • sheep(100913155) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • domestic guinea pig(100720162) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • naked mole-rat(101721168) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Zebrafish(336252) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • domestic cat(101094237) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • cow(540657) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Domestic Rabbit(100356357) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Horse(100059608) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • chicken(414890) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • dog(489146) gamma-aminobutyric acid (GABA) A receptor, beta 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Thiopental, United States Pharmacopeia (USP) Reference Standard,
Species
human
Propofol, British Pharmacopoeia (BP) Reference Standard,
Species
human
Propofol, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
SR-95531, ≥98% (HPLC), powder,
Species
human
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse
2,6-Diisopropylphenol, 97%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABA A Receptor beta 2 (GABRB2) Antibody, clone 6G9O8, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17, clone BD17, Chemicon®, from mouse,
Species Reactivity
bovine, feline, human, monkey, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-GABRB2 Antibody, clone BD17 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, feline, human, monkey, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GABA A Receptor β2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
Species Reactivity
bovine, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
Anti-GABRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GABRB2,
Species
human
MISSION® esiRNA, targeting mouse Gabrb2,
Species
mouse