C237
(2S,1′S,2′S)-2-(Carboxycyclopropyl)glycine
solid
Synonym(s):
L-CCG-1
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About This Item
Empirical Formula (Hill Notation):
C6H9NO4
CAS Number:
Molecular Weight:
159.14
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
solid
color
white
solubility
H2O: >7 mg/mL
SMILES string
N[C@@H]([C@H]1C[C@@H]1C(O)=O)C(O)=O
Gene Information
human ... GRM1(2911), GRM2(2912), GRM3(2913), GRM4(2914), GRM5(2915), GRM7(2917), GRM8(2918)
rat ... Grm1(24414), Grm2(24415), Grm6(24419)
Biochem/physiol Actions
Potent group II metabotropic glutamate receptor agonist.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Chew L Lau et al.
Neurochemical research, 35(5), 735-742 (2010-02-10)
Astrocytic excitatory amino acid transporters (EAATs) regulate excitatory transmission and limit excitotoxicity. Evidence for a functional interface between EAATs and glial fibrillary acidic protein (GFAP) relevant to astrocytic morphology led to investigations of actions of transportable (D-Aspartate (D-Asp) and (2S,3S,4R)-2-(carboxycyclopropyl)glycine
Michael Meredith et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(25), 5719-5725 (2004-06-25)
Chemosignals related to reproductive and social status (pheromones) carry messages between opposite-sex and same-sex individuals in many species. Each individual must distinguish signals relevant to its own social behavior with conspecifics from signals used by other (heterospecific) species relevant to
M Llansola et al.
Neuroscience, 133(1), 185-191 (2005-05-17)
Hyperammonemia impairs signal transduction associated to glutamate receptors and phosphorylation of some neuronal proteins including microtubule-associated protein 2 (MAP-2). The aim of this work was to analyze the effects of hyperammonemia on modulation of MAP-2 phosphorylation by metabotropic glutamate receptors