ANTXR1
anthrax toxin receptor 1
别名:
ATR, GAPO, TEM8
物种:
Human ANTXR1 (84168), Mouse Antxr1 (69538), Rat Antxr1 (362393), naked mole-rat Antxr1 (101701494), domestic guinea pig Antxr1 (100728514), sheep ANTXR1 (101108204), Domestic Rabbit ANTXR1 (100357637), cow ANTXR1 (616010), domestic cat ANTXR1 (101092930), Horse ANTXR1 (100061334) ...展开
UniProtKB ID:
基因ID:
- Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
- Mouse(69538) anthrax toxin receptor 1
- Rat(362393) anthrax toxin receptor 1
- naked mole-rat(101701494) anthrax toxin receptor 1
- domestic guinea pig(100728514) anthrax toxin receptor 1
- sheep(101108204) anthrax toxin receptor 1
- Domestic Rabbit(100357637) anthrax toxin receptor 1
- cow(616010) anthrax toxin receptor 1
- domestic cat(101092930) anthrax toxin receptor 1
- Horse(100061334) anthrax toxin receptor 1
- dog(612601) anthrax toxin receptor 1
- chicken(428199) anthrax toxin receptor 1
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