CNTF
ciliary neurotrophic factor
别名:
HCNTF
物种:
Human CNTF (1270), Mouse Cntf (12803), Rat Cntf (25707), domestic cat CNTF (101097592), chicken CNTF (396488), Domestic Rabbit CNTF (100009117), domestic guinea pig Cntf (100724905), naked mole-rat Cntf (101713822), dog CNTF (483464), cow CNTF (100848228)
UniProtKB ID:
基因ID:
- Human(1270) Summary: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
- Mouse(12803) ciliary neurotrophic factor
- Rat(25707) ciliary neurotrophic factor
- domestic cat(101097592) ciliary neurotrophic factor
- chicken(396488) ciliary neurotrophic factor
- Domestic Rabbit(100009117) ciliary neurotrophic factor
- domestic guinea pig(100724905) ciliary neurotrophic factor
- naked mole-rat(101713822) ciliary neurotrophic factor
- dog(483464) ciliary neurotrophic factor
- cow(100848228) ciliary neurotrophic factor
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