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Merck
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GPS2

G protein pathway suppressor 2

别名:
AMF-1
物种:
UniProtKB ID:
基因ID:
  • Human(2874) Summary: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
  • Mouse(56310) G protein pathway suppressor 2
  • Rat(497941) G protein pathway suppressor 2
  • Zebrafish(393948) G protein pathway suppressor 2
  • cow(518494) G protein pathway suppressor 2
  • naked mole-rat(101716315) G protein pathway suppressor 2
  • domestic guinea pig(100716061) G protein pathway suppressor 2
  • sheep(101119059) G protein pathway suppressor 2
  • domestic cat(101096521) G protein pathway suppressor 2
  • dog(607730) G protein pathway suppressor 2

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
说明
物种反应性
应用
Anti-GPS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Monoclonal Anti-GPS2 antibody produced in mouse, clone 3C4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Gps2,
物种
mouse