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Merck
CN

IL7R

interleukin 7 receptor

别名:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
物种:
UniProtKB ID:
基因ID:
  • Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
  • Mouse(16197) interleukin 7 receptor
  • Rat(294797) interleukin 7 receptor
  • Zebrafish(100134973) interleukin 7 receptor
  • chicken(426054) interleukin 7 receptor
  • dog(612582) interleukin 7 receptor
  • domestic cat(101100697) interleukin 7 receptor
  • Horse(100034169) interleukin 7 receptor
  • naked mole-rat(101710077) interleukin 7 receptor
  • sheep(101111126) interleukin 7 receptor
  • Domestic Rabbit(100343726) interleukin 7 receptor
  • domestic guinea pig(100714027) interleukin 7 receptor
  • cow(521554) interleukin 7 receptor
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esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting human IL7R,
物种
human