PCDHGB5
protocadherin gamma subfamily B, 5
别名:
PCDH-GAMMA-B5
物种:
Human PCDHGB5 (56101), Mouse Pcdhgb5 (93702), Rat Pcdhgb5 (680448), sheep PCDHGB5 (101103812), chicken PCDHGB5 (776350), cow PCDHGB5 (100337166), dog PCDHGB5 (607624), Horse PCDHGB5 (100072229), domestic cat PCDHGB5 (101099683), cow PCDHGB5 (101903816)
UniProtKB ID:
基因ID:
- Human(56101) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
- Mouse(93702) protocadherin gamma subfamily B, 5
- Rat(680448) protocadherin gamma subfamily B, 5
- sheep(101103812) protocadherin gamma subfamily B, 5
- chicken(776350) protocadherin gamma subfamily B, 5
- cow(100337166) protocadherin gamma subfamily B, 5
- dog(607624) protocadherin gamma subfamily B, 5
- Horse(100072229) protocadherin gamma subfamily B, 5
- domestic cat(101099683) protocadherin gamma subfamily B, 5
- cow(101903816) protocadherin gamma subfamily B, 5
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