POF1B
premature ovarian failure, 1B
别名:
POF, POF2B
物种:
Human POF1B (79983), Mouse Pof1b (69693), Rat Pof1b (302328), Zebrafish pof1b (564098), cow POF1B (614768), sheep POF1B (101102041), chicken POF1B (422268), domestic cat POF1B (101098524), domestic guinea pig Pof1b (100729730), naked mole-rat Pof1b (101698475)
UniProtKB ID:
基因ID:
- Human(79983) Summary: Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called 'POF1' and 'POF2' have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010]
- Mouse(69693) premature ovarian failure 1B
- Rat(302328) premature ovarian failure 1B
- Zebrafish(564098) premature ovarian failure, 1B
- cow(614768) premature ovarian failure, 1B
- sheep(101102041) premature ovarian failure, 1B
- chicken(422268) premature ovarian failure, 1B
- domestic cat(101098524) premature ovarian failure, 1B
- domestic guinea pig(100729730) premature ovarian failure, 1B
- naked mole-rat(101698475) premature ovarian failure, 1B
- dog(491994) premature ovarian failure, 1B
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Antibodies
产品编号
说明
物种反应性
应用
Anti-POF1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry