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Merck
CN

PTPN7

protein tyrosine phosphatase, non-receptor type 7

别名:
BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI
物种:
UniProtKB ID:
基因ID:
  • Human(5778) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(320139) protein tyrosine phosphatase, non-receptor type 7
  • Rat(246781) protein tyrosine phosphatase, non-receptor type 7
  • cow(614077) protein tyrosine phosphatase, non-receptor type 7
  • sheep(101114718) protein tyrosine phosphatase, non-receptor type 7
  • domestic guinea pig(100723664) protein tyrosine phosphatase, non-receptor type 7
  • naked mole-rat(101715531) protein tyrosine phosphatase, non-receptor type 7
  • chicken(770905) protein tyrosine phosphatase, non-receptor type 7
  • dog(607227) protein tyrosine phosphatase, non-receptor type 7
  • Horse(100052261) protein tyrosine phosphatase, non-receptor type 7
  • domestic cat(101098110) protein tyrosine phosphatase, non-receptor type 7

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Antibodies

产品编号
说明
物种反应性
应用
Anti-PTPN7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-PTPN7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
proximity ligation assay
western blot

Proteins

产品编号
说明
物种
HePTP Protein, 250 µg, ,
物种
human

esiRNA

产品编号
说明
物种
MISSION® esiRNA, targeting mouse Ptpn7,
物种
mouse
MISSION® esiRNA, targeting human PTPN7,
物种
human