SELPLG
selectin P ligand
别名:
CD162, CLA, PSGL-1, PSGL1
物种:
Human SELPLG (6404), Mouse Selplg (20345), Rat Selplg (363930), domestic guinea pig Selplg (100712957), Horse SELPLG (100034025), chicken SELPLG (772212), Zebrafish selplg (100884146), sheep SELPLG (101102589), cow SELPLG (617434), domestic cat SELPLG (101087945) ...展开
UniProtKB ID:
基因ID:
- Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
- Mouse(20345) selectin, platelet (p-selectin) ligand
- Rat(363930) selectin P ligand
- domestic guinea pig(100712957) selectin P ligand
- Horse(100034025) selectin P ligand
- chicken(772212) selectin P ligand
- Zebrafish(100884146) selectin P ligand
- sheep(101102589) selectin P ligand
- cow(617434) selectin P ligand
- domestic cat(101087945) selectin P ligand
- dog(611673) selectin P ligand
- naked mole-rat(101713908) selectin P ligand
No matching products for sirna. Please clear filter
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.